Cholestyramineresin 考来烯胺
CAS 11041-12-6 MFCD00130784
化学结构图
SMILES:
别名和识别编码
| Synonym | Dowex® 1X2 Cl--形态 Colestyramine Dowex® 1X2 Cl--Form Colestyramin Polystyrene benzyltrimethylaminonium chloride Cholestyramine resin Dowex® 1X2 Cl--形态 消胆胺 Cholestyramine chloride; Cholestyramine hydroxide; Cholestyramine resin; Cholybar; Colestyramin; Colestyramine; Cuemid; MK 135; Quantalan; Questran Quantalan Cuemid 消胆胺 消胆胺树脂 Cholestyramine chloride |
|---|---|
| MDL Number | MFCD00130784 |
| CAS Number | 11041-12-6 |
| EC Number | 234-270-8 |
| Chemical Name | Cholestyramineresin |
| Chemical Name Translation | 考来烯胺 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- {SNA} Anion Exchange Media, Ion Exchange Chromatography, Protein Chromatography, Proteomics
- Anion Exchange Media, Ion Exchange Chromatography, Protein Chromatography, Proteomics
- {SNA} Anion Exchange Media, Ion Exchange Chromatography, 分子生物学, 蛋白质组学, 蛋白质色谱
相关文献及参考
- Rigamonti, A.E., et al., The cholestyramine-induced decrease of PYY postprandial response is negatively correlated with fat mass in obese women. Horm. Metab. Res. 43 , 569-573, (2011) 摘要
- Danley, T. and St. Anna, L., Clinical inquiry. Postcholecystectomy diarrhea: what relieves it? J. Fam. Pract. 60 , 632c-632d, (2011)
- Fuhrmann, V., et al., Extracorporeal artificial liver support systems in the management of intractable cholestatic pruritus. Liver Int. 3 , 31-33, (2011)
- Merck 14 ,2202
安全信息
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - man DOSE/DURATION : 112 gm/kg/W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - colon tumors REFERENCE : NEJMAG New England Journal of Medicine. (Massachusetts Medical Soc., 10 Shattuck St., Boston, MA 02115) V.198- 1928- Volume(issue)/page/year: 301,1007,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >3 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,412,1990
TYPE OF TEST : TDLo - Lowe
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - child DOSE/DURATION : 46 gm/kg/39W-I TOXIC EFFECTS : Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Blood - hemorrhage REFERENCE : CMAJAX Canadian Medical Association Journal. (Canadian Medical Assoc., POB 8650, Ottawa, ON K1G 0G8, Canada) V.1- 1911- Volume(issue)/page/year: 134,609,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : >3 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Human - infant DOSE/DURATION : 42 gm/kg/7W-I TOXIC EFFECTS : Blood - eosinophilia REFERENCE : CPEDAM Clinical Pediatrics (Philadelphia). (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1962- Volume(issue)/page/year: 20,675,1981
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 42 gm/kg
SEX/DURATION : male 9 week(s) pre-mating
female 2 week(s) pre-mating
female 1-7 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda
Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960-
Volume(issue)/page/year: 16,2040,1982TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 5500 mg/kg SEX/DURATION : female 7-17 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 16,2050,1982
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE : 6 gm/kg SEX/DURATION : female 17-22 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - sex ratio Reproductive - Effects on Newborn - physical REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 16,2078,1982
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE : 13 gm/kg SEX/DURATION : fem
