Cholera Toxin from Vibrio cholerae Cholera

CAS 9012-63-9 MFCD00130776

化学结构图

9012-63-9
SMILES:

别名和识别编码

Synonym Vibrio cholerae exotoxin CTX Cholera enterotoxin Cholergen Cholera enterotoxin Cholergen Cholera exotoxin 霍乱菌素; 霍乱毒素 Choleragen Cholera toxin exo-Enterotoxin Cholera enterotoxin Cholergen Cholera entero-exotoxin
MDL NumberMFCD00130776
CAS Number9012-63-9
Chemical NameCholera Toxin from Vibrio cholerae
Chemical Name TranslationCholera
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Bacteria, Bioactive Small Molecules, C-CH, Cell Signaling and Neuroscience, G Protein Function, G Proteins and Cyclic Nucleotides, Reagents,
  • Bacteria, Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience, G Protein Function, G Proteins and Cyclic Nucleotides, Reagents, Toxins and Venoms
  • {SNA} Bacteria, Bioactive Small Molecule Alphabetical Index, C-CH, G Protein Function, G Proteins and Cyclic Nucleotides, Reagents, Toxins and Venoms, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • [2]. Tsai SC, et al. Stimulation of choleragen enzymatic activities by GTP and two soluble proteins purified from bovine brain. J Biol Chem. 1988;263(4):1768-1772.
  • [3]. Wernick NL, et al. Cholera toxin: an intracellular journey into the cytosol by way of the endoplasmic reticulum. Toxins (Basel). 2010;2(3):310-325.
  • Andersen, S.M., et al., Topical Application Of Valrubicin Has A Beneficial Effect On Developing Skin Tumors. Carcinogenesis 31 , 1483-90, (2010) 摘要
  • Androutsellis-Theotokis, A., et al., Cholera Toxin Regulates A Signaling Pathway Critical For The Expansion Of Neural Stem Cell Cultures From The Fetal And Adult Rodent Brains. PLoS ONE 5 , e10841, (2010) 摘要
  • Debnath, J., Detachment-induced Autophagy In Three-dimensional Epithelial Cell Cultures. Meth. Enzymol. 452 , 423-39, (2009) 摘要
  • Evers, D.L., et al., The Liposome PCR Assay Is More Sensitive Than The Vibrio Cholerae Enterotoxin And Escherichia Coli Heat-labile Enterotoxin R

安全信息

WGK Germany2
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P301+P310
  • P302+P350
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P301+P310+P330
  • P302+P352+P310
Hazard Codes T Xn
Hazard statements
  • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
  • H300+H310
GHS Symbol
Signal word Danger
Safety Statements
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
Risk Statements
  • R52/53
  • R24/25 Toxic in contact with skin and if swallowed 皮肤接触及吞食都有毒
RTECSLF3100000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 260 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IMLCAV Immunological Communications.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1972-  Volume(issue)/page/year: 1,223,1972

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 19,701,1981

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 10 ug/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Olfaction) - effect, not otherwise
   specified
   Behavioral - food intake (animal)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 18,309,1980

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - mouse Cells - not otherwise specified
DOSE/DURATION           : 10 ug/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 8,377,1987

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 40 ug/kg
SEX/DURATION            : female 8-10 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 45,315,1975

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 8 ug/kg
SEX/DURATION            : female 4-6 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Fertility - abortion
REFERENCE :
   IMLCAV Immunological Communications.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1972-  Volume(issue)/page/year: 1,223,1972

系列性分类


相关产品推荐