Botulinum toxin A

CAS 93384-43-1 MFCD00130667

化学结构图

93384-43-1
SMILES:

别名和识别编码

MDL NumberMFCD00130667
Chemical NameBotulinum Toxin A from Clostridium botulinum
Synonym Neurotoxin, Botulinum A Toxine botulinique A Botulinum Toxin A from Clostridium botulinum Botulinum A neurotoxin Botulin toxin
CAS Number93384-43-1
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分类

  • {SNA} B, Bacteria, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Neurobiology, Neuroscience, Pharmacologicals, Toxins, Toxins and Venoms

安全信息

RTECSED9300000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4 ng/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 24,1065,1986

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1250 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
REFERENCE :
   JPHYA7 Journal of Physiology.  (Cambridge Univ. Press, 32 E. 57th St., New
   York, NY 10022) V.1-    1878-  Volume(issue)/page/year: 260,177,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 30 pg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IGAYAY Igaku No Ayumi.  Progress in Medicine.  (Ishiyaku Shuppan K.K.,
   1-7-10, Honkomagom, Bunkyo-ku, Tokyo, Japan)  V.1-    1946-
   Volume(issue)/page/year: 112,861,1980

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 160 ng/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   28,227,1974

GHS Symbol
WGK Germany2
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P301+P310
Signal word Danger
Hazard Codes Xn
Risk Statements
  • R22 Harmful if swallowed 吞咽有害

系列性分类


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