5-Ethyl-2-(2-Hydroxyethyl)Pyridine 5-乙基-2-(2-羟基乙基)吡啶
CAS 5223-06-3 MFCD00129040
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Building Blocks, C9, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines
- Bases & Related Reagents
- {KO} Alcohols
- Aromatics
- Nucleotides
产品应用
- 重要的有机中间体,主要用于治疗Ⅱ型糖尿病药品吡格列酮的中间原料。
相关文献及参考
- Beilstein:21(5)2,260
安全信息
GHS Symbol
- S000926
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- R000921
- R21 Harmful in contact with skin 与皮肤接触有害
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P264+P265
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P352
- P302+P352+P312+P362+P364
- P304+P340
- P305+P351+P338
- P305+P351+P338+P337+P313
- P305+P354+P338
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
- P317
- P319
- P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
- P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
- P332+P313
- P337+P313
- P337+P317
- P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
- P362+P364
- P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
- P403+P233
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H303 May be harmfully swallowed 吞食可能有害
- H312 Harmful in contact with skin 皮肤接触有害
- H318 Causes serious eye damage 严重伤害眼睛
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4290 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 1780 uL/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
药物吸收、分布、代谢与排泄(ADME)
Lipinski's Rule of 3
Y
Lipinski's Rule of 5
Y
H-bond Acceptors
2
Rotatable Bonds
3
H-bond Donors
1
LogP
1
其他信息
- 5-乙基-2-吡啶乙醇价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 E0562 5-乙基-2-吡啶乙醇 5-Ethyl-2-pyridineethanol 5G 588元 2014/06/02 E0562 5-乙基-2-吡啶乙醇 5-Ethyl-2-pyridineethanol 25G 1710元 2010/05/25 L19482 5-乙基-2-(2-羟基乙基)吡啶, 98% 5-Ethyl-2-(2-hydroxyethyl)pyridine, 98% 5g 584元
- 外观性质:无色或淡黄色液体。沸点:127°C
- TCI Shanghai:5-乙基-2-吡啶乙醇 5-Ethyl-2-pyridineethanol,>;97.0%(GC)(5223-06-3)
- 用途一:用作医药中间体
- Alfa Aesar:5-乙基-2-(2-羟基乙基)吡啶,98% 5-Ethyl-2-(2-hydroxyethyl)pyridine, 98%(5223-06-3)
- 用途二:重要的有机中间体,主要用于治疗Ⅱ型糖尿病药品吡格列酮的中间原料。
- MOL 文件:5223-06-3.mol
- 上游原料:乙醇 --> 三氯甲烷 --> 甲酸 --> 多聚甲醛 --> 对叔丁基邻苯二酚 --> 5-乙基-2-甲基-吡啶