Azoxymethane 氧化偶氮甲烷
CAS 25843-45-2 MFCD00126912
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- {SNA} Cancer Research, Carcinogens
- {SNA} Carcinogens, 癌症研究, 细胞生物学
- {SNA} 癌症研究, 细胞生物学, 致癌物
安全信息
GHS Symbol
- H350 May cause cancer 可能致癌
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H226 Flammable liquid and vapour 易燃液体和蒸气
- H300 Fatal if swallowed 吞食致命
- H290 May be corrosive to metals 可能腐蚀金属。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P301+P310
- P308+P313
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P305+P351+P338
- P301+P310+P330
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P337+P313
- P370+P378
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S35 This material and its container must be disposed of in a safe way 该物料及其容器必须以安全方式处置;
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
- R46 May cause inheritable genetic damage 可能引起遗传基因损害
- R10 Flammable 易燃
- R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
- R45 May cause cancer 可能致癌
- R25 Toxic if swallowed 吞咽有毒
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 20 mg/kg/(22D TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Peripheral Nerve and Sensation - peripheral nerv
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - hamster DOSE/DURATION : 60 mg/kg/20W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 47,3968,1987
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3200 ug/kg TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Gastrointestinal - colon tumors REFERENCE : VTPHAK Veterinary Pathology. (Waverly Press, Inc., POB 64025, Baltimore, MD 21264) V.8- 1971- Volume(issue)/page/year: 12,165,1975
TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 37 mg/kg/10W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Gastrointestinal - colon tumors REFERENCE : JAVMA4 Journal of the American Veterinary Medical Association. (American Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.48- 1915- Volume(issue)/page/year: 164,729,1974
TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 27 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : XENOBH Xenobiotica. (Taylor & Francis Ltd., 4 John St., London WC1N 2ET, UK) V.1- 1971- Volume(issue)/page/year: 3,271,1973
TYPE OF TEST : Unscheduled DNA synthesis ROUTE OF EXPOSURE : Oral TEST SYSTEM : Rodent - rat DOSE/DURATION : 10 mg/kg REFERENCE : ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 4,553,1982
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TYPE OF TEST : DNA damage ROUTE OF EXPOSURE : Oral TEST SYSTEM : Rodent - rat DOSE/DURATION : 10 mg/kg REFERENCE : ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 4,667,1982
TYPE OF TEST : Sex chromosome loss and nondisjunction ROUTE OF EXPOSURE : Unreported TEST SYSTEM : Insect - Drosophila melanogaster DOSE/DURATION : 1 mmol/L/3D (Continuous) REFERENCE : DRISAA Drosophila Information Service. (Cold Spring Harbor Laboratory, POB 100, Cold Spring Harbor, NY 11724) No.1- 1934- Volume(issue)/page/year: 50,138,1973
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 10 ug/plate REFERENCE : ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 6(Suppl 2),1,1984
TYPE OF TEST : Sex chromosome loss and nondisjunction ROUTE OF EXPOSURE : Oral TEST SYSTEM :
TYPE OF TEST : Body fluid assay TEST SYSTEM : Rodent - rat Bacteria - Salmonella typhimurium DOSE/DURATION : 12800 ug/kg REFERENCE : PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 72,4607,1975
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE : 30 mg/kg SEX/DURATION : female 14 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetal death REFERENCE : IARCCD IARC Scientific Publications. (Geneva, Switzerland) No.1-26, 1971-78. For publisher information, see IAPUDO. Volume(issue)/page/year: 4,45,1973
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE : 30 mg/kg SEX/DURATION : female 15 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetal death REFERENCE : IARCCD IARC Scientific Publications. (Geneva, Switzerland) No.1-26, 1971-78. For publisher information, see IAPUDO. Volume(issue)/page/year: 4,45,1973