(R)-(-)-Α-Methylhistamine (Dihydrochloride) (R)-1-(1H-咪唑-4-基)丙-2-胺二盐酸盐
CAS 75614-89-0 MFCD00083176
化学结构图
SMILES: Cl.Cl.C[C@@H](N)CC1=CNC=N1
化学属性
| Mol. Formula | C6H11N3· 2HCl |
|---|---|
| Mol. Weight | 198.09 |
别名和识别编码
| Chemical Name | (R)-(-)-Α-Methylhistamine (Dihydrochloride) |
|---|---|
| Synonym | (R)(-)-α-Methyl-1H-imidazole-4-ethanamine dihydrochloride (R)(-)-α-Methyl-1H-imidazole-4-ethanamine dihydrochloride (R)(-)-α-Methylhistamine dihydrochloride |
| CAS Number | 75614-89-0 |
| PubChem Substance ID | 24277778 |
| MDL Number | MFCD00083176 |
| Chemical Name Translation | (R)-1-(1H-咪唑-4-基)丙-2-胺二盐酸盐 |
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分类
- {SNA} Agonists, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Histaminergics, M, Membrane Protein Biology
- {SNA} Agonists, Bioactive Small Molecule Alphabetical Index, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Histaminergics, M, Membrane Protein Biology Tools, Mistaminergics - Agonists, Neuroscience, Neurotransmission, Neurotransmitters, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细
相关文献及参考
- Oishi, et al., Effects of the histamine H 3 -agonist (R)-α-methylhistamine and the antagonist thioperamide on histamine metabolism in the mouse and rat brain. J. Neurochem. 52 , 1388, (1989) 摘要
- Arrang, J. M., et al., Highly potent and selective ligands for histamine H 3 -receptors. Nature 327 , 117, (1987) 摘要
- Gerhard, et al., Structure-activity relations of histamine analogs. XX. Absolute configuration and histamine-like activity of enantiomeric α-methyl histamines. Arch. Pharm. Res. 313 , 709, (1980)
安全信息
GHS Symbol
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
