Sauvagine

CAS 74434-59-6 MFCD00081983

化学结构图

74434-59-6
SMILES: [H]/N=C(\N)/NCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCN/C(/N)=N/[H])NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(N)=O

化学属性

Mol. Weight4599.31
Mol. FormulaC202H346N56O63S

别名和识别编码

MDL NumberMFCD00081983
CAS Number74434-59-6
Chemical NameSauvagine
Synonym Sauvagine
Chemical Name Translation
InChIKeyILCVKEBXPLEGOY-ZLFMSJRASA-N
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分类

  • Bioactive Small Molecules, CRF, Cell Biology, Cell Signaling and Neuroscience,
  • {SNA} CRF, Neuropeptides, Other Releasing Factors, Parathyroid Hormone Fragments, Peptides and Proteins, Peptides for Cell Biology, Releasing Factors, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Bioactive Small M

相关文献及参考

  • [2]. P C Montecucchi, et al. Amino acid composition and sequence analysis of sauvagine, a new active peptide from the skin of Phyllomedusa sauvagei. Int J Pept Protein Res. 1981 Aug;18(2):113-20.
  • [3]. M H Perrin, et al. Corticotropin releasing factor receptors and their ligand family. Ann N Y Acad Sci. 1999 Oct 20;885:312-28.
  • Eckart, K., et al., Actions of CRF and its analogs. Curr. Med. Chem. 6 , 1035-1053, (1999) 摘要
  • Kosoyan, H.P., et al., Intracisternal sauvagine is more potent than corticotropin-releasing factor to decrease gastric vagal efferent activity in rats. Peptides 20 , 851-858, (1999) 摘要
  • Renda, T., et al., Brain-gut-skin peptides: an update overview. Arch. Histol. Cytol. , 317-323, (1989) 摘要
  • [1]. David A Lovejoy, e
  • [1]. David A Lovejoy, et al. Evolution and phylogeny of the corticotropin-releasing factor (CRF) family of peptides: expansion and specialization in the vertebrates. J Chem Neuroanat. 2013 Dec;54:50-6.

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类


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