CAS 9011-18-1 MFCD00081551-Dextran Sulfate Sodium 葡聚糖硫酸钠 TAO{mole}

Dextran Sulfate Sodium 葡聚糖硫酸钠

CAS 9011-18-1 MFCD00081551

化学结构图

SMILES: *C[C@H]1O[C@H](O*)[C@H](OS(=O)(=O)[O-])[C@@H](OS(=O)(=O)[O-])[C@@H]1OS(=O)(=O)[O-].[Na+].[Na+].[Na+]

化学属性

Mol. Weight	-
Mol. Formula	N/A
TSCA	Yes
Density	1.23
Stability	易吸潮

别名和识别编码

MDL Number	MFCD00081551
CAS Number	9011-18-1
Synonym	MDS (polysaccharide) Asuro Dexulate 葡聚糖硫酸酯钠盐来源于明串珠菌属 Dextran sodium sulfate 葡聚糖硫酸氢钠;糖酐酯 Dexnon Sodium dextran sulfate Dextrarine 硫酸葡聚糖钠盐; 葡聚糖硫酸钠; 葡聚糖硫酸酯钠 MDS Dextran, hydrogen sulfate, sodium salt Dextran sulfate sodium salt DS-M-1 葡聚糖硫酸氢钠,糖酐酯,硫酸葡聚糖钠盐硫酸葡聚糖
Chemical Name	Dextran Sulfate Sodium
Merck Number	2951
EC Number	250-023-7
Beilstein Registry Number	2384789
PubChem Substance ID	87568245
Chemical Name Translation	葡聚糖硫酸钠

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分类

{SNA} Biochemicals, Blocking Reagents for Hybridization, Carbohydrate adjuvants, Core Bioreagents, Dextran Sulfates for General Research Applications, Dextrans, General Reagents, Life Science Reagents for Northern and Southern Blotting, Nucleic Acid Hybridization Reagents, Research Essentials, Vaccine Adjuvants,
{SNA} Carbohydrates,

产品应用

降血脂和抗动脉粥样硬化药

安全信息

WGK Germany2

RTECSHH9290000

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

Signal word Warning

GHS Symbol

Safety Statements

S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P305+P351+P338

Storage condition 储存温度2-8°C,充氩保存 2-8℃保存,充氩保存 0-10°C 0-10 2-8℃保存储存温度2-8°C

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 645 gm/kg/31W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - colon tumors
REFERENCE :
   CRTXB2 CRC Critical Reviews in Toxicology.  (CRC Press, Inc., 2000 Corporate
   Blvd., NW, Boca Raton, FL 33431)  V.1-    1971- Volume(issue)/page/year:
   17,215,1987

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 600 gm/kg/69W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - colon tumors
   Endocrine - tumors
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   18,29,1983

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 335 gm/kg/19W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Gastrointestinal - colon tumors
REFERENCE :
   JJIND8 JNCI, Journal of the National Cancer Institute.  (Washington, DC)
   V.61-79, 1978-87. For publisher information, see JNCIEQ.
   Volume(issue)/page/year: 66,579,1981

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 330 gm/kg/94W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Gastrointestinal - colon tumors
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 3,

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 19 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,481,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 473 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 13,1318,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 20600 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 13,1318,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2350 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   KSRNAM Kiso

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES