Tranylcypromine 反式-2-苯基环丙胺半硫酸盐
CAS 13492-01-8 MFCD00079222
化学结构图
SMILES: N[C@@H]1C[C@H]1c1ccccc1.N[C@@H]1C[C@H]1c1ccccc1.O=S(=O)(O)O
化学属性
| Mol. Formula | C9H11N · 1/2H2SO4 |
|---|---|
| Mol. Weight | 182.23 |
别名和识别编码
| Chemical Name | Tranylcypromine |
|---|---|
| Synonym | Tranylcypromine 反式-2-苯基环丙胺 半硫酸盐 Phenylcyclopromine sulfate trans,D,L-2-Phenylcyclopropylamine sulfate Tranylcypromine sulfate (+-)-trans-2-Phenylcyclopropylamine sulfate (2:1) Parnate Cyclopropanamine, 2-phenyl-, trans-(+-)-, sulfate (2:1) 1-Amino-2-phenylcyclopropane sulfate Tranylcypromine sulphate 反苯环丙胺 |
| MDL Number | MFCD00079222 |
| CAS Number | 13492-01-8 |
| EC Number | 236-807-1 |
| Wiswesser Line Notation | L3TJ AZ BR 2 &..H2.S-O4 |
| Chemical Name Translation | 反式-2-苯基环丙胺半硫酸盐 |
| PubChem Substance ID | 329820106 |
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分类
- {SNA} Application Index, Bioactiv
- {SNA} Application Index, Bioactive Small Molecule Alphabetical Index, Cell Signaling Enzymes, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme,
- {SA} Application Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes, Cell Signaling and Neuroscience,
相关文献及参考
- Merck 14 ,9573
安全信息
GHS Symbol
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P301+P310
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
- H331 Toxic if inhaled 吸入中毒
- H311 Toxic in contact with skin 皮肤接触中毒
- H300 Fatal if swallowed 吞食致命
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 45 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 18,617,1967
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 41 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year: 6,115,1969
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - man DOSE/DURATION : 34 mg/kg/60D-I TOXIC EFFECTS : Peripheral Nerve and Sensation - paresthesis Musculoskeletal - joints REFERENCE : AJPSAO American Journal of Psychiatry. (American Psychiatric Assoc., Circulation Dept., 1400 K St., NW, Washington, DC 20005) V.78- 1921- Volume(issue)/page/year: 140,1229,1983
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF E
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE/DURATION : 1200 ug/kg/3D-I TOXIC EFFECTS : Vascular - BP lowering not characterized in autonomic section REFERENCE : AJPSAO American Journal of Psychiatry. (American Psychiatric Assoc., Circulation Dept., 1400 K St., NW, Washington, DC 20005) V.78- 1921- Volume(issue)/page/year: 144,119,1987
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
