Sodium 3-(((5-(4-Nitrophenyl)Furan-2-Yl)Methylene)Amino)-2,5-Dioxoimidazolidin-1-Ide 3-(((5-(4-硝基苯基)呋喃-2-基)亚甲基)氨基)-2,5-二氧代咪唑啉-1-鎓钠盐
CAS 14663-23-1 MFCD00079130
化学结构图
SMILES: [Na+].[O-]C1=NC(=O)CN1/N=C/C1=CC=C(O1)C1C=CC(=CC=1)[N+]([O-])=O
化学属性
| Mol. Formula | C14H9N4NaO5·xH2O |
|---|---|
| Mol. Weight | 336.24(as Anhydrous) |
| TSCA | No |
别名和识别编码
| Chemical Name | Sodium 3-(((5-(4-Nitrophenyl)Furan-2-Yl)Methylene)Amino)-2,5-Dioxoimidazolidin-1-Ide |
|---|---|
| Synonym | F-400 2,4-Imidazolidinedione, Dantrolene sodium Dantrium 1-[[[5-(4-硝基苯)-2-呋喃基]亚甲基氨基]-2,4-咪唑啉二酮 钠盐 丹曲林 钠盐 Dantorolene sodium |
| MDL Number | MFCD00079130 |
| PubChem Substance ID | 125307729 |
| EC Number | 238-706-8 |
| CAS Number | 14663-23-1 |
| Merck Number | 2816 |
| Chemical Name Translation | 3-(((5-(4-硝基苯基)呋喃-2-基)亚甲基)氨基)-2,5-二氧代咪唑啉-1-鎓钠盐 |
| Reaxys-RN | 5698800 |
| Wiswesser Line Notation | T5OJ BR DNW& E1UN- AT5NVMV EHJ &-NA- |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, D-DIF, Intracellular Calcium Regulators, Intracellular Calcium Signaling, JHP Pharmaceuticals
- {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, D-DIF, Intracellular Calcium Regulators,
安全信息
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- S22 Do not breathe dust 不要吸入粉尘；
- R60 May impair fertility 可能降低生殖能力
- R61 May cause harm to the unborn child 可能对未出生的婴儿导致伤害
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 534 mg/kg TOXIC EFFECTS : Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 11,3065,1977
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 7432 mg/kg TOXIC EFFECTS : Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 11,3065,1977
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 413 mg/kg TOXIC EFFECTS : Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 11,3065,1977
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : >10550 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Toky
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Human - woman DOSE : 3143 ug/kg SEX/DURATION : female 39 week(s) after conception TOXIC EFFECTS : Reproductive - Maternal Effects - uterus, cervix, vagina REFERENCE : AACRAT Anesthesia and Analgesia (New York). (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.36- 1957- Volume(issue)/page/year: 66,269,1987
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 500 mg/kg
SEX/DURATION : female 14 day(s) pre-mating
female 7-17 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
gain)
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda
Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960-
Volume(issue)/page/year: 11,2218,1977TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE : 260 mg/kg SEX/DURATION : female 6-18 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 11,2212,1977
