CAS 41859-67-0 MFCD00078970-2-(4-(2-(4-Chlorobenzamido)Ethyl)Phenoxy)-2-Methylpropanoic Acid 2-(4-(2-(4-氯苯甲酰胺)乙基)苯氧基)-2-甲基丙酸 TAO{mole}

2-(4-(2-(4-Chlorobenzamido)Ethyl)Phenoxy)-2-Methylpropanoic Acid 2-(4-(2-(4-氯苯甲酰胺)乙基)苯氧基)-2-甲基丙酸

CAS 41859-67-0 MFCD00078970

化学结构图

SMILES: CC(C)(OC1=CC=C(CCNC(=O)C2C=CC(Cl)=CC=2)C=C1)C(O)=O

化学属性

Mol. Formula	C19H20ClNO4
Mol. Weight	362
TSCA	No
Melting Point	182.0 to 186.0 deg-C

别名和识别编码

Chemical Name	2-(4-(2-(4-Chlorobenzamido)Ethyl)Phenoxy)-2-Methylpropanoic Acid
CAS Number	41859-67-0
Synonym	2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropanoic acid Bezafibrate Bezafibrato
MDL Number	MFCD00078970
PubChem Substance ID	87560846
EC Number	255-567-9
Merck Number	1195
Chemical Name Translation	2-(4-(2-(4-氯苯甲酰胺)乙基)苯氧基)-2-甲基丙酸
Reaxys-RN	4267656
Wiswesser Line Notation	QVX1&1&OR D2MVR DG
Beilstein Registry Number	4267656
LabNetwork Molecule ID	LN00008010

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品牌质保精细包装现货库存一流品牌服务

产品应用

Antilipemic.

安全信息

WGK Germany1

GHS Symbol

Hazard statements

H302 Harmful if swallowed 吞食有害

RTECSUE8755000

Signal word

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

Safety Statements

Hazard Codes Xn

Risk Statements

Precautionary statements

P301+P312+P330
P501 Dispose of contents/container to..… 处理内容物/容器.....
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 723 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 22,4293,1988

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1580 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory depression
   Gastrointestinal - tumors
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha C

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 1326 mg/kg/37W-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
REFERENCE :
   LANCAO Lancet.  (7 Adam St., London WC2N 6AD, UK)  V.1-    1823-
   Volume(issue)/page/year: 341,371,1993

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - chronic pulmonary edema
   Gastrointestinal - other changes
   Liver - other changes
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd.

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 3900 mg/kg
SEX/DURATION            : female 6-18

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 8800 mg/kg
SEX/DURATION            : female 7-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - sex ratio
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 22,4415,1988

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 550 mg/kg
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 22,4415,1988

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       :

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1 gm/kg
SEX/DURATION            : female 17-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - stillbirth
   Reproductive - Effects on Newborn - live birth index (measured after birth)
   Reproductive - Effects on Newborn - other neonatal measures or effects
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 22,4433,1988