CGS 21680 HYDROCHLORIDE 3-(4-(2-((6-氨基-9-((2R,3R,4S,5S)-5-(乙基氨甲酰)-3,4-二羟基四氢呋喃-2-基)-9H-嘌呤-2-基)氨基)乙基)苯基)丙酸
CAS 120225-54-9 MFCD00078573
化学结构图
SMILES: Cl.CCNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2C(N)=NC(NCCC3=CC=C(CCC(O)=O)C=C3)=NC1=2
化学属性
| Mol. Formula | C23H29N7O6.ClH |
|---|---|
| Mol. Weight | 535.986 |
别名和识别编码
| Chemical Name | CGS 21680 HYDROCHLORIDE |
|---|---|
| Chemical Name Translation | 3-(4-(2-((6-氨基-9-((2R,3R,4S,5S)-5-(乙基氨甲酰)-3,4-二羟基四氢呋喃-2-基)-9H-嘌呤-2-基)氨基)乙基)苯基)丙酸 |
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相关文献及参考
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- [4]. Melani A, et al. Low doses of the selective adenosine A2A receptor agonist CGS21680 are protective in a rat model of transient cerebral ischemia. Brain Res. 2014 Mar 10;1551:59-72.
- [5]. Komaki S, et al. Trk and cAMP-dependent survival activity of adenosine A(2A) agonist CGS21680 on rat motoneurons in culture. Neurosci Lett. 2012 Jul 26;522(1):21-4.
- [1]. Bao R, et al. Adenos
- [1]. Bao R, et al. Adenosine and the adenosine A2A receptor agonist, CGS21680, upregulate CD39 and CD73 expression through E2F-1 and CREB in regulatory T cells isolated from septic mice. Int J Mol Med. 2016 Sep;38(3):969-75.
