A-3 Hydrochloride A3 盐酸盐
CAS 78957-85-4 MFCD00077311
化学结构图
SMILES: Cl.NCCNS(=O)(=O)C1C=CC=C2C(Cl)=CC=CC=12
化学属性
| Mol. Formula | C12H14Cl2N2O2S |
|---|---|
| Mol. Weight | 321 |
别名和识别编码
| Chemical Name | A-3 Hydrochloride |
|---|---|
| CAS Number | 78957-85-4 |
| Synonym | A-3 N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide hydrochloride |
| MDL Number | MFCD00077311 |
| PubChem Substance ID | 24890609 |
| Chemical Name Translation | A3 盐酸盐 |
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分类
- {SNA} A-AM, Bioactive Small Molecules, Casein Kinase (CK), Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors
- {SNA} A-AM, Bioactive Small Molecule Alphabetical Index, Casein Kinase (CK), Kinase/Phosphatase Biology, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- A-AM, Bioactive Small Molecules, Casein Kinase (CK), Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Serine/Threonine Kinase Biology, Se
产品应用
- Inhibits cAMP and cGMP dependent protein kinases. Also inhibits MLC kinase and protein kinase C.
相关文献及参考
- Inagaki, M., et al.: Mol. Pharmacol., 29, 577 (1986)
- Inagaki, N., et al. , Naphthalenesulfonamides as calmodulin antagonists and protein kinase inhibitors. Mol. Pharmacol. 29 , 577-581 , (1986) 摘要
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
