[β-Mercapto-β,β-cyclopentamethylenepropionyl1, O-Et-Tyr2, Val4, Arg8]-Vasopressin
CAS 77453-01-1 MFCD00076752
化学结构图
SMILES: CC(C)[C@@H]1NC(=O)[C@H](CC2C=CC=CC=2)NC(=O)[C@H](CC2C=CC(=CC=2)OCC)NC(=O)CC2(CCCCC2)SSC[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O
化学属性
| Mol. Formula | C53H75N13O11S2 |
|---|---|
| Mol. Weight | 1134.37 |
别名和识别编码
| Chemical Name | [β-Mercapto-β,β-cyclopentamethylenepropionyl1, O-Et-Tyr2, Val4, Arg8]-Vasopressin |
|---|---|
| MDL Number | MFCD00076752 |
| CAS Number | 77453-01-1 |
| Synonym | [β-Mercapto-β,β-cyclopentamethylenepropionyl1, O-Et-Tyr2, Val4, Arg8]-Vasopressin |
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资金保障
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分类
- Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Oxytocin & Vasopressin, Peptides and Proteins, Peptides for Cell Biology, Pituitary Hormones, V, Vasopressin, Vasopressins
- {SNA} Cytokines, Growth Factors and Hormones, Hormones, Oxytocin & Vasopressin, Peptides and Proteins, Peptides for Cell Biology, Pituitary Hormones, Vasopressin, Vasopressins, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factor
相关文献及参考
- Ammar, A., et al., Pharmacological characterization of V1a vasopressin receptors in the rat cortical collecting duct. Am. J. Physiol. 262 , F546-F553, (1992) 摘要
- Champigneulle, A., et al., V2-like vasopressin receptor mobilizes intracellular Ca 2+ in rat medullary collecting tubules. Am. J. Physiol. 265 , (1993)
- Chan, W.Y., et al., Discovery and design of novel and selective vasopressin and oxytocin agonists and antagonists: the role of bioassays. Exp. Physiol. 85 , 7S-18S, (2000) 摘要
- Manning, M., et al., Position three in vasopressin antagonist tolerates conformationally restricted and aromatic amino acid substitutions: a striking contrast with vasopressin agonists. J. Pept. Sci. 3 , 31-46, (1997) 摘要
- [1]. S Ishikawa, et al. Further in vivo evidence for antagonist-to-antidiuretic action of arginine vasopressin. Am J Physiol. 1983 Nov;245(5 Pt 1):R713-9.
安全信息
GHS Symbol
- H332 Harmful if inhaled 吸入有害
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R20 Harmful by inhalation 吸入有害
