4-Acetyl-N-[(cyclohexylamino)carbonyl]benzenesulfonamide 1-[(对乙酰苯)磺酰]-3-环己脲
CAS 968-81-0 MFCD00072156
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分类
- {SNA} A, A-AM, AA to AL, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Bioactive Small Molecules, 细胞生物学
- Sulfur & Selenium Compounds
- {SNA} A, A-AM, AA to AL, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Bioactive Small Molecules, Cell Biology
- Pharmaceuticals
- A
- Intermediates & Fine Chemicals
- {SNA} Additional Drugs, Analytical Standards, Pharmaceuticals, Illicit Drugs & Alcohol, 分析/色谱
- {SNA} A, A-AM, AA to AL, Alphabetical Index of Analytical Standards, Analytical Standards,
产品应用
- Acetohexamide is a sulfonylurea derivative. Acetohexamide is a hyopglycemic agent with moderate uricosuric activity. Acetohexamide is a first generation medication used in the treatment of diabetes m
相关文献及参考
- Yu, T-F. et al.: Metab. Clin. Exp., 17, 309 (1968); Harrower, A.D.B. et al.: Clin. Pharmacokin., 31, 111 (1996); Hirota, Y. et al.: Diab. Med., 26, 948 (2009);
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,34,1995
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >2500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,18,1982
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Human - woman DOSE : 900 mg/kg SEX/DURATION : female 26-39 week(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - stillbirth REFERENCE : BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 2,187,1964