CAS 144-74-1 MFCD00072133-Sodium ((4-Aminophenyl)Sulfonyl)(Thiazol-2-Yl)Amide ((4-氨基苯基)磺酰)(噻唑-2-基)酰胺钠盐 TAO{mole}

Sodium ((4-Aminophenyl)Sulfonyl)(Thiazol-2-Yl)Amide ((4-氨基苯基)磺酰)(噻唑-2-基)酰胺钠盐

CAS 144-74-1 MFCD00072133

化学结构图

SMILES: Nc1ccc(S(=O)(=O)N([Na])c2nccs2)cc1

化学属性

Mol. Formula	C9 H8 N3 O2 S2 . Na
Mol. Weight	277.298
Boiling Point	-
Flash Point	-

别名和识别编码

Chemical Name	Sodium ((4-Aminophenyl)Sulfonyl)(Thiazol-2-Yl)Amide
MDL Number	-
CAS Number	144-74-1
Synonym	(n(sup1)-2-thiazolylsulfanilamido)-sodiu 2-Sulfanilamidothiazole sodium salt 2-对氨基苯磺酰胺噻唑 LABO Monosodium 2-sulfanilamidothiazole N(sup 1)-2-Thiazolylsulfanilamide sodium salt SULFATHIAZOLE SULFATHIAZOLE SODIUM SULFATHIAZOLE SODIUM SALT Sodium 2-sulfanilamidothiazole Sodium norsulfazole Sodium sulfathiazole Sodium sulphathiazole Sulfanilamide, N(sup 1)-2-thiazolyl-, N(sup 1)-sodium deriv. Sulfathiazole Sodium Salt {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {
Beilstein Registry Number	3802297
EC Number	205-638-5
PubChem Substance ID	12285822
Chemical Name Translation	((4-氨基苯基)磺酰)(噻唑-2-基)酰胺钠盐
Wiswesser Line Notation	T5N CSJ BMSWR DZ &-NA-
InChI	InChI=1S/C9H8N3O2S2.Na/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9;/h1-6H,10H2;/q-1;+1
LabNetwork Molecule ID	LN01871780
Canonical SMILES	-

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安全信息

GHS Symbol

WGK Germany2

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P305+P351+P338

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛
H335 May cause respiratory irritation 可能导致呼吸道刺激

RTECSWP2450000

Signal word Warning

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes Xi

Safety Statements

S36 Wear suitable protective clothing 穿戴适当的防护服；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾；
S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
   Volume(issue)/page/year: 45,15,1940

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1320 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 81,284,1944

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1950 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
   Volume(issue)/page/year: 43,328,1940

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 708 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JIDXA3 Journal of the Indiana State Medical Association.  (Indiana State
   Medical Assoc., 3935 N. Meridian, Indianapolis, IN 46208)  V.1-    1908-
   Volume(issue)/page/year: 33,503,1940

TYPE OF TEST

{h

Storage condition -20 -20°C -20°C, Hygroscopic -20℃

其他信息

用途一:属磺胺类药，用于治疗敏感菌感染
MOL 文件:144-74-1.mol
Sigma Aldrich:144-74-1(sigmaaldrich)
F:10