CAS 4345-03-3 MFCD00072055-D-α-Tocopherol succinate, 96%, reference material D-α-生育酚琥珀酸酯 TAO{mole}

D-α-Tocopherol succinate, 96%, reference material D-α-生育酚琥珀酸酯

CAS 4345-03-3 MFCD00072055

化学结构图

SMILES: Cc1c(C)c2c(c(C)c1OC(=O)CCC(=O)O)CC[C@@](C)(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)O2

化学属性

Mol. Formula	C33H54O5
Mol. Weight	530.78
Melting Point	73-77
Density	1.002
Stability	对热敏感
Solubility	Soluble in DMSO, chloroform (50 mg/ml), and ethanol. Insoluble in water

别名和识别编码

Chemical Name	D-α-Tocopherol succinate, 96%, reference material
CAS Number	4345-03-3
Synonym	D-α-Tocopherol Succinate {LY} D-α-Tocopherol Succinate {} {LY} D-α-Tocopherol Succinate {} {} {LY} D-α-Tocopherol Succinate {} {} {} {LY} D-α-Tocopherol Succinate {} {} {} {} {LY} D-α-Tocopherol Succinate {} {} {} {} {} {LY} D-α-Tocopherol Succinate {} {} {} {} {} {} {LY} D-α-Tocopherol Succinate {} {} {} {} {} {} {} {LY} D-α-Tocopherol Succinate {} {} {} {} {} {} {} {} {LY} D-α-Tocopherol Succinate {} {} {} {} {} {} {} {} {} {LY} D-α-Tocopherol Succinate {} {} {} {} {} {} {} {} {} {} {LY} D-α-Tocopherol Succinate {} {} {} {} {} {} {} {} {} {} {} {LY} D-α-Tocopherol Succinate {} {} {} {} {} {} {} {} {} {} {} {} {LY} D-α-Tocopherol Succinate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} D-α-Tocopherol Succinate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} D-α-Tocopherol Succinate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} D-α-Tocopherol Succinate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} D-α-Tocopherol Suc
MDL Number	MFCD00072055
PubChem Substance ID	20353
Beilstein Registry Number	4038233
EC Number	224-403-8
Chemical Name Translation	D-α-生育酚琥珀酸酯
Merck Number	9495
Reaxys-RN	65995
LabNetwork Molecule ID	LN00196324
InChI	InChI=1S/C33H54O5/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-20-33(8)21-19-28-27(7)31(25(5)26(6)32(28)38-33)37-30(36)18-17-29(34)35/h22-24H,9-21H2,1-8H3,(H,34,35)/t23-,24-,33-/m1/s1
Canonical SMILES	CC1=C2C(CC[C@](C)(O2)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)=C(C(OC(CCC(O)=O)=O)=C1C)C

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产品应用

A potent antioxidant tocopherol

安全信息

WGK Germany1

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

RTECSEJ9984000

Storage condition -20°C {LY} -20°C 0-10°C 2-8°C {} {LY} -20°C {} {} {LY} -20°C {} {} {} {LY} -20°C {} {} {} {} {LY} -20°C {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY}

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >7 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAFCAU Journal of Agricultural and Food Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1953-  Volume(issue)/page/year: 25,273,1977

GHS Symbol

Safety Statements

S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；

Hazard statements

其他信息

D-α-Tocopheryl Succinate is a potent antioxidant tocopherol. At high concentrations it has been shown to trigger caspase-mediated apoptosis of certain cells and, at low concentrations, inhibit proliferation. Mechanistic studies suggest that this compound down-regulates the fibroblast growth factor receptor-1 (FGFR1). Other experiments report that D-α-Tocopheryl Succinate also targets ASK 1, GADD 45β, and MEK-4, three key components of stress-activated mitogen-activated protein kinase pathway.
F:8-10-23
MOL 文件:4345-03-3.mol
MSDS 信息:D-alpha-Tocopherol succinate(4345-03-3).msds
Sigma Aldrich:4345-03-3(sigmaaldrich)