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分类

• {SNA} Allium cepa (Onion), Allium sativum (Garlic), Aloe Vera, Antioxidant and Free Radical Scavengers, Antioxidants and Cytoprotectants, Berberis sp., Biochemicals and Reagents, Carthamus tinctorius (Safflower oil), Cell Stress, Chemopreventive Agents, Elettaria Cardamomum (Cardamom), Euterpe oleracea (Acai), Hordeum vulgare (Barley), Humulus lupulus (Hops), Linum usitatissimum (Flax), Lipids, Nitric Oxide and Cell Stress, Olea europaea (Olive), Phytochemicals by Plant (Food/Spice/Herb), Prenols, T, Vaccinium macrocarpon (Cranberry), Vitamin E,
• {SNA} Companion Products and Reagents,

产品应用

• ?-Tocopherol is the most bioactive of the naturally occurring forms of Vitamin E. Richest sources are green vegetables, grains, and oils, particularly palm, safflower and sunflower oils.

相关文献及参考

• [2]. Daiki Hayashi, et al. Amelioration of diabetic nephropathy by oral administration of d-α-tocopherol and its mechanisms. Biosci Biotechnol Biochem. 2018 Jan;82(1):65-73.
• [3]. Atchara Paemanee, et al. Screening of melatonin, α-tocopherol, folic acid, acetyl-L-carnitine and resveratrol for anti-dengue 2 virus activity. BMC Res Notes. 2018 May 16;11(1):307.
• Bianchi, G., et al.: Eur. J. Lipid Sci. Technology, 105, 229 (2003),
• Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publ
• Short: IV/15A Title: Diffusion in Gases, Liquids and Electrolytes: Gases in Gases, Liquids and their Mixtures Author: Winkelmann, J Editor: Lechner, Manfred Dieter Source: Landolt-Börnstein, New Series Volume: IV/15A Year: 2007 Keyword: binary mix

安全信息

GHS Symbol

TYPE OF TEST            : DNA adduct
ROUTE OF EXPOSURE       : Intravenous
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 27 nmol/kg
REFERENCE :
   EXPEAM Experientia.  (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
   Switzerland)  V.1-    1945-  Volume(issue)/page/year: 31,1023,1975

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 100 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   45,337,1985

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 7500 mg/kg
SEX/DURATION            : female 1-20 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   69,293,1973

其他信息

• MOL 文件:59-02-9.mol
• 检测方法:GC
• 下游产品:生育酚乙酸酯
• 存储注意事项:光敏感;氩气保护
• Acros Organics:D-alpha-生育酚/D-alpha-维生素e D-alpha-Tocopherol, 99%(59-02-9)
• 上游原料:乙酐 --> 异植物醇 --> 三甲基氢醌
• 参考质量标准二:FAO/WHO，1992 生育酚总量 ≥40% 其中d-α-生育酚(C29H50O2) ≥95%(方法同“01036'’) 硫酸盐灰分 尚待调研 砷(GT-3-2) ≤3mg/kg 重金属(GT-16-2，试样0.5g) ≤40mg/kg 铅(GT-18) ≤10mg/kg 比旋光度([α] D 25 ) ≥+24° 酸度(同“01035，dl-α-生育酚”) 正常
• 用途一:用于维生素E缺乏所致的流产、习惯性流产及先兆性流产的预防，也用于不育症及婴儿营养性巨细胞贫血等病治疗
• Sigma Aldrich:59-02-9(sigmaaldrich)
• 毒性:天然食品，无毒。 ADI 0.15～2(FAO/WHO，2001)；不作特殊规定(EEC，1986)。 GRAS (FDA §182．3890； §182．5890；§182．8890；2000)。
• 天然维生素 E价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 T2309 D-α-生育酚 D-alpha-Tocopherol 25G 397元 2010/06/21 421031000 天然维生素 E D-alpha-Tocopherol 99% 100 MG 854元
• 使用限量:以适度为限(FDA§184.1890，2000)。 按GB 14880—94，可用于芝麻油、色拉油、人造奶油、乳制品100～180mg；婴幼儿食品40～70mg。 按GB 2760 2002的规定，同“01035，dl-α-生育酚”。
• TCI Shanghai:D-维生素E D-alpha-Tocopherol,>;97.0%(GC)(59-02-9)
• 比旋光度:24 ° (c=2, in isooctane 25 °C)
• F:8-10-23
• 参考质量标准一:FCC，1996 指标名称 高α型 低α型 总生育酚 ≥50.0% ≥50.0% d-α-生育酚(C29H50O2) ≥50.9％ - d-β-与d-γ-(C28H48O2)和d-δ-生育酚(C27H46O2)的总量 ≥20.0% - d-β-与d-γ-和d-δ-生育酚的总量 - ≥80.0% 重金属(以Pb计)(GT-16-2) 10mg/kg 10mg/kg 比旋光度[α] D 25 ≥+24° ≥+20° 酸度试验 正常 正常 QB 2483—2000 指标 高d-α-生育酚 E50型 E70型 低d-α-生育酚 d-α-醋酸生育酚 含量 总生育粉/%≥ 50.0 70.0 50.0 - d-α-生育酚/%≥ 95.0 95.0 - - d-β-, d-γ-和d-δ-生育酚%≥ - - 80.0 - d-α-醋酸生育酚/%≥ - - - 96.0-102.0 酸度／ml≤ 1.0 0.5 比旋度[α] D 25℃ ≥ +24° +20° +24° 重金属(以Pb计)/mg/kg≤ 10 过氧化值/meq/kg≤ 10
• color:clear yellow
• MSDS 信息:(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol(59-02-9).msds