Meglumine Amidotrizoate 氨基三丙酸甲葡胺
CAS 131-49-7 MFCD00069632
化学结构图
SMILES: CC(=O)Nc1c(I)c(NC(C)=O)c(I)c(C(=O)O)c1I.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
化学属性
| Mol. Formula | C18H26I3N3O9 |
|---|---|
| Mol. Weight | 614 |
别名和识别编码
| Chemical Name | Meglumine Amidotrizoate |
|---|---|
| MDL Number | MFCD00069632 |
| CAS Number | 131-49-7 |
| Synonym | Amidotrizoate meglumine Angiografin Benzoic acid, 3,5-diacetamido-2,4,6-triiodo-, compd. with Meglumine diatrizoate N-Methyl-D-glucamine diatrizoate |
| PubChem Substance ID | 8566 |
| EC Number | 205-024-7 |
| Chemical Name Translation | 氨基三丙酸甲葡胺 |
| Wiswesser Line Notation | 1VMR BI DI FI CVQ EMV1 &Q1YQYQYQYQ1M1 |
| InChI | InChI=1S/C11H9I3N2O4.C7H17NO5/c1-3(17)15-9-6(12)5(11(19)20)7(13)10(8(9)14)16-4(2)18;1-8-2-4(10)6(12)7(13)5(11)3-9/h1-2H3,(H,15,17)(H,16,18)(H,19,20);4-13H,2-3H2,1H3/t;4-,5+,6+,7+/m.0/s1 |
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分类
- {SNA} Density Gradient Media, Hematology and Histology, Histopaque and Nonionic Iodinated Density Gradient Media, Other Nonionic Iodinated
- {SNA} Cell Biology, Density Gradient Media, Hematology and Histology, Histopaque and Nonionic Iodinated Density Gradient Media, Other Nonionic Iodinated
- {SNA} Density Gradient Media, Hematology and Histology, Histopaque and Nonionic Iodinated Density Gradient Media, Other Nonionic Iodinated, 细胞生物学
- {SNA} Density Gradient Media, Nonionic Iodinated Density Gradient Media, 细胞生物学, 血液学和组织学
- {SNA} Density Gradient Media, Histopaque and Nonionic Iodinated Density Gradient Media, Other Nonionic Iodinated, 细胞生物学, 血液学和组织学
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 19500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- Volume(issue)/page/year: 26,921,1984
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 14565 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AAJRDX AJR, American Journal of Roentgenology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.126- 1976- Volume(issue)/page/year: 142,619,1984
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Human - man DOSE/DURATION : 214 mg/kg TOXIC EFFECTS : Kidney, Ureter, Bladder - changes in both tubules and glomeruli Kidney, Ureter, Bladder - interstitial nephritis Kidney, Ureter, Bladder - urine volume decreased REFERENCE : 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,392,1969
TYPE OF
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Parenteral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 44504 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AAJRDX AJR, American Journal of Roentgenology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.126- 1976- Volume(issue)/page/year: 142,619,1984
