Normorphine
CAS 466-97-7 MFCD00069318
化学结构图
SMILES: Oc1ccc2c3c1O[C@H]1[C@@H](O)C=C[C@H]4[C@@H](C2)NCC[C@]314
化学属性
| Mol. Formula | C16H17NO3 |
|---|---|
| Mol. Weight | 271.34 |
别名和识别编码
| Chemical Name | Morphinan-3,6-alpha-diol,7,8-didehydro-4,5-alpha-epoxy- |
|---|---|
| CAS Number | 466-97-7 |
| Synonym | N-Normorphine Demethylmorphine Normorphine NSC 270042 (5?,6?)-7,8-Didehydro-4,5-epoxy-morphinan-3,6-diol Desmethylmorphine 4,5-Epoxy-3,6-dihydromorphin-7-ene N-Demethylmorphine (-)-Normorphine |
| MDL Number | MFCD00069318 |
| PubChem Substance ID | 24897470 |
| EC Number | 207-381-4 |
| Beilstein Registry Number | 5297209 |
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分类
- Metabolites & Impurities
- Pharmaceuticals
- Intermediates & Fine Chemicals,
- {SNA} Alkaloids, Alphabetic, Analytical Standards, Analytical/Chromatography, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, Forensic and Veterinary Standards, Morphine, N, NJ - NZ, Neat Compounds
产品应用
- Normorphine is a metabolite of Morphine (M652290).
相关文献及参考
- Coffman, B., et al.: Drug Metab. Dispos., 25, 1 (1997),
- Hanks, G., et al.: Br. J. Cancer, 84, 587 (2001),
- Projean, D., et al.: Xenobiotica, 33, 841 (2003),
安全信息
GHS Symbol
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P284 Wear respiratory protection.? 佩戴呼吸保护装置。
- P302+P350
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- H330 Fatal if inhaled 吸入致命
- H310 Fatal in contact with skin 皮肤接触致命
- H300 Fatal if swallowed 吞食致命
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 104 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 17,433,1961
