sodium ((4-aminophenyl)sulfonyl)(pyrimidin-2-yl)amide 磺胺嘧啶钠
CAS 547-32-0 MFCD00067333
化学结构图
SMILES: Nc1ccc(S(=O)(=O)N([Na])c2ncccn2)cc1
化学属性
| Mol. Formula | C10H9N4NaO2S |
|---|---|
| Mol. Weight | 272.26 |
| Density | 1.496 |
| Boiling Point | 512.6°C at 760 mmHg |
| Flash Point | 263.8°C |
| Melting Point | >300°C |
别名和识别编码
| Chemical Name | sodium ((4-aminophenyl)sulfonyl)(pyrimidin-2-yl)amide |
|---|---|
| MDL Number | MFCD00067333 |
| CAS Number | 547-32-0 |
| Synonym | Sulfadiazine (sodium) {Chemicalbook} 4-AMINO-N-[2-PYRIMIDINYL]BENZENESULFONAMIDE SODIUM SALT 4-amino-n-2-pyrimidinyl-benzenesulfonamidmonosodiumsalt 4-氨基-N-(2-嘧啶基)苯磺酰胺 钠盐 SPS 琼脂添加剂 Benzenesulfonamide, 4-amino-N-2-pyrimidinyl-, monosodium salt Monosodium 2-sulfanilamidopyrimidine N(sup 1)-2-Pyrimidinylsulfanilamide monosodium salt PERFRINGENS SUPPLEMENT I PERFRINGENS SUPPLEMENT I FOR MICRO-BIOL SODIUM 4-AMINO-N-PYRIMIDIN-2-YL-BENZENESULFONAMIDE SODIUM SULFADIAZINE SPS AGAR SUPPLEMENT SULFADIAZINE SODIUM SULFADIAZINE SODIUM (SD-NA) SULFADIAZINE SODIUM SALT SULFADIAZINESODIUM,USP Sodium sulfadiazi {} {Chemicalbook} 2-sulfanilamidopyrimidinesodiumsalt {} {} {hazard_com} 2-Sulfanilamidopyrimidine sodium salt {} {} {} {Chemicalbo |
| PubChem Substance ID | 15899898 |
| Beilstein Registry Number | 4068213 |
| EC Number | 208-919-0 |
| Chemical Name Translation | 磺胺嘧啶钠 |
| Wiswesser Line Notation | T6N CNJ BMSWR DZ &-NA- |
| LabNetwork Molecule ID | LN01806119 |
| InChI | InChI=1S/C10H9N4O2S.Na/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1 |
| Canonical SMILES | O=S(C1=CC=C(N)C=C1)(N([Na])C2=NC=CC=N2)=O |
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分类
- {SNA} Analytical Standards, Antibiotics Standards, Pharmaceuticals, Illicit Drugs & Alcohol, 分析/色谱
- {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, S, SN - SZ
产品应用
- 磺胺类抗菌消炎药，用于治疗禽霍乱、伤寒、白痢、脑脊髓炎、败血症、弓形虫感染；注射用。
相关文献及参考
安全信息
GHS Symbol
- P342+P311
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
- H302 Harmful if swallowed 吞食有害
- H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H319 Causes serious eye irritation 严重刺激眼睛
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- S22 Do not breathe dust 不要吸入粉尘；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R22 Harmful if swallowed 吞咽有害
- R42/43
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1700 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 94,338,1953
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1747 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 81,17,1944
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 540 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 94,338,1953
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1408 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AMSSAQ Acta Medica Scandinavica, Supplement. (Almqvist & Wiksell, POB 45150, S-10430 Stockholm, Sweden) No.1-730, 1921-88. Volume(issue)/page/year: 142,64,1943
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE : 1440 mg/kg SEX/DURATION : female 1 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - other neonatal measures or effects REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 101,362,1951
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Multiple routes SPECIES OBSERVED : Rodent - mouse DOSE : 2400 mg/kg SEX/DURATION : female 6-7 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - other neonatal measures or effects REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 101,362,1951
其他信息
- 无臭，味微苦；遇光色渐变暗；易溶于水，微溶于乙醇，水溶液遇酚酞指示液显碱性反应。
- MOL 文件:547-32-0.mol
- Sigma Aldrich:547-32-0(sigmaaldrich)
- 用途一:磺胺类抗菌消炎药，用于治疗禽霍乱、伤寒、白痢、脑脊髓炎、败血症、弓形虫感染；注射用。
- F:10-21
- 外观性质:白色结晶性粉末，无臭，味微苦；遇光色渐变暗；易溶于水，微溶于乙醇，水溶液遇酚酞指示液显碱性反应。
- 磺胺嘧啶钠价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 SS638701 磺胺嘧啶钠盐 25g 235元
