(1S,5R)-10,10-Dimethyl-3-Thia-4-Azatricyclo[5.2.1.0(1,5)]Decane 3,3-Dioxide (-)-10,2-樟脑磺内酰胺

CAS 94594-90-8 MFCD00066271

化学结构图

94594-90-8
SMILES: CC1(C)[C@H]2C[C@H]3NS(=O)(=O)C[C@@]13CC2

化学属性

Mol. FormulaC10H17NO2S
Mol. Weight215
Melting Point182.0 to 186.0 deg-C
TSCANo
Density1.422

别名和识别编码

Chemical Name(1S,5R)-10,10-Dimethyl-3-Thia-4-Azatricyclo[5.2.1.0(1,5)]Decane 3,3-Dioxide
CAS Number94594-90-8
Alfabeta NameCAMPHORSULTAM S1210(())----,
MDL NumberMFCD00066271
Synonym (-)-exo-10,2-莰烷磺内酰胺 (1S,5R)-10,10-二甲基-3-硫杂-4-氮杂三环[5.2.1.01,5]癸烷-3,3-二氧化物 (2R)-(-)-Bornane-10,2-sultam (-)-10,2-樟脑磺内酰胺 (-)-exo-10,2-莰烷磺内酰胺 (1S,5R)-10,10-二甲基-3-硫杂-4-氮杂三环[5.2.1.01,5]癸烷-3,3-二氧化物 [3aS-(3aα,6α,7aβ)]-六氢-8,8-二甲基-3H-3a,6-亚甲基-2,1-苯并异噻唑基-2,2-二氧化物 Hexahydro-8,8-dimethyl-3H-3a,6-methano-2,1-benzisothiazole (1S)-(-)-2,10-樟脑磺内酰胺 (2R)-Bornane-10,2-sultam (-)-10,2-樟脑磺内酰胺 (-)-exo-10,2-莰烷磺内酰胺 (1S,5R)-10,10-二甲基-3-硫杂-4-氮杂三环[5.2.1.01,5]癸烷-3,3-二氧化物 [3aS-(3aα,6α,7aβ)]-六氢-8,8-二甲基-3H-3a,6-亚甲基-2,1-苯并异噻唑基-2,2-二氧化物 (-)-10,2-樟脑磺内酰胺 (1S)-(-)-10,2-Camphorsultam
PubChem Substance ID87566338
Beilstein Registry Number27(3/4)1007
EC Number250-023-7
Chemical Name Translation(-)-10,2-樟脑磺内酰胺
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分类

  • Sulfur & Selenium Compounds
  • Chiral Reagents
  • {SNA} Asymmetric Synthesis, Chemical Synthesis, Chiral Auxiliaries, Sulfur-Based
  • {SA} Asymmetric Synthesis, Chemical Synthesis, Chiral Auxiliaries, Sulfur-Based

产品应用

  • Reagent used to make Camphorsultam conjugates.

相关文献及参考

  • Inoue, M., et al.: Nat. Chem., 2, 280 (2010),
  • Beilstein:27(3/4)1007
  • Springthorpe, B., et al.: Bioorg. Med. Chem. Lett., 17, 6013 (2007),

安全信息

Warnings IRRITANT
WGK Germany3
GHS Symbol
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P302+P352+P332+P313+P362+P364
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P332+P313
  • P305+P351+P338+P337+P313
  • P302+P350
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Hazard Codes Xi

系列性分类


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