D-Pyroglutamic acid (R)-(+)-2-吡咯烷酮-5-羧酸

CAS 4042-36-8 MFCD00066212

化学结构图

4042-36-8
SMILES: O=C1CC[C@H](C(=O)O)N1

化学属性

Mol. FormulaC5H7NO3
Mol. Weight129.11
Density1.38
Melting Point155-162°C
TSCANo
Solubility可溶
Refractive index10 ° (C=5, H2O)
Boiling Point453.1°C at 760 mmHg

别名和识别编码

Chemical Name(R)-2-Pyrrolidinone-5-carboxylic Acid
CAS Number4042-36-8
Synonym (R)-5-Oxopyrrolidine-2-carboxylic acid {LY} (R)-5-Oxopyrrolidine-2-carboxylic acid {} {LY} (R)-5-Oxopyrrolidine-2-carboxylic acid {} {} {LY} (R)-5-Oxopyrrolidine-2-carboxylic acid {} {} {} {LY} (R)-5-Oxopyrrolidine-2-carboxylic acid {} {} {} {} {LY} (R)-5-Oxopyrrolidine-2-carboxylic acid {} {} {} {} {} {LY} (R)-5-Oxopyrrolidine-2-carboxylic acid {} {} {} {} {} {} {LY} (R)-5-Oxopyrrolidine-2-carboxylic acid {} {} {} {} {} {} {} {LY} (R)-5-Oxopyrrolidine-2-carboxylic acid {} {} {} {} {} {} {} {} {LY} (R)-5-Oxopyrrolidine-2-carboxylic acid {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {LY} (R)-5-Oxopyrrolidine-2-carboxylic acid {} {} {} {} {} {} {} {} {} {} {LY} (R)-5-Oxopyrrolidine-2-carboxylic acid {} {} {} {} {} {} {} {} {} {} {} {LY} (R)-5-Oxopyrrolidine-2-carboxylic acid {} {} {} {} {} {} {} {} {} {} {} {} {LY} (R)-5-Oxopyrrolidine-2-carboxylic acid {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} (R)-5-Oxopyrrolidine
MDL NumberMFCD00066212
EC Number223-735-0
Beilstein Registry Number22(5)6,7
PubChem Substance ID439685
Reaxys-RN82133
Merck Number8001
Chemical Name Translation(R)-(+)-2-吡咯烷酮-5-羧酸
InChIKeyODHCTXKNWHHXJC-GSVOUGTGSA-N
LabNetwork Molecule IDLN00239891
InChIInChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m1/s1
Canonical SMILESO=C(O)[C@@H](CC1)NC1=O
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分类

  • Amino Acids & Derivatives
  • Chiral Reagents
  • {SNA} Chemical Biology, Chemical Synthesis, Other Unnatural Amino Acids & Derivatives, Peptide Chemistry, Unnatural Amino Acids & Derivatives
  • {SNA} Chemical Biology, Chemical Synthesis, Others, Peptide Chemistry, Unnatural Amino Acids & Derivatives
  • {SNA} Chemical Biology, Chemical Synthesis, Others, Peptide Chemistry, Unnatural Amino Acid Derivatives

产品应用

  • Serves as a building block in the synthesis of diphthamide.

相关文献及参考

  • Beilstein:22(5)6,7
  • Evans, D.A. and Lundy, K.M.: J. Am. Chem. Soc., 114, 1495 (1992)
  • For applications, see next entry.

安全信息

Signal word
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P304+P340
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P305+P354+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P317
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xi
Storage condition 2-8°C {LY} 2-8°C Store at 0-5°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C

其他信息

  • Acros Organics:D-焦谷氨酸 (R)-(+)-2-Pyrrolidone-5-carboxylic acid, 98+%(4042-36-8)
  • D-焦谷氨酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 P1354 D-焦谷氨酸 D-Pyroglutamic Acid 5G 409元 2014/06/02 P1354 D-焦谷氨酸 D-Pyroglutamic Acid 25G 1240元 2010/06/21 243090100 D-焦谷氨酸 (R)-(+)-2-Pyrrolidone-5-carboxylic acid 98+% 10 GR 1328元
  • 检测方法:Rotation,T,NMR
  • 比旋光度:27.5 ° (c=10,1N NaOH)
  • MOL 文件:4042-36-8.mol
  • Sigma Aldrich:4042-36-8(sigmaaldrich)
  • Alfa Aesar:(R)-(+)-2-吡咯烷酮-5-羧酸,98+% (R)-(+)-2-Pyrrolidinone-5-carboxylic acid, 98+%(4042-36-8)
  • TCI Shanghai:D-焦谷氨酸 D-Pyroglutamic Acid,>;98.0%(T)(4042-36-8)

系列性分类


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