1-((5-Chloronaphthalen-1-yl)sulfonyl)-1,4-diazepane hydrochloride 1-((5-氯萘-1-基)磺酰基)-1,4-二氮杂环庚烷盐酸盐
CAS 105637-50-1 MFCD00065525
化学结构图
SMILES: Cl.O=S(=O)(C1C=CC=C2C(Cl)=CC=CC=12)N1CCCNCC1
化学属性
| Mol. Formula | C15H17N2O2SCl · HCl |
|---|---|
| Mol. Weight | 361.29 |
别名和识别编码
| Chemical Name | 1-((5-Chloronaphthalen-1-yl)sulfonyl)-1,4-diazepane hydrochloride |
|---|---|
| CAS Number | 105637-50-1 |
| Synonym | 1-(5-Chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride ML-9 |
| MDL Number | MFCD00065525 |
| PubChem Substance ID | 24278297 |
| Chemical Name Translation | 1-((5-氯萘-1-基)磺酰基)-1,4-二氮杂环庚烷盐酸盐 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Kinase/Phosphatase Biology, L to O, M, Myosin Light Chain Kinase, Myosin Light Chain Kinase (MLCK), P to Q, Protein Kinase Inhibitors, Protein kinase A, Protein kinase C, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物
- Protein Kinase Inhibitors and Activators
- {SNA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors,
产品应用
- Inhibits the catalytic activities of several protein kinases competitively with respect to ATP and exhibited different Ki values toward each protein kinase. Also found to be a new type of vascular re
相关文献及参考
- [2]. Shaikh S, et al. The STIM1 inhibitor ML9 disrupts basal autophagy in cardiomyocytes by decreasing lysosome content.Toxicol In Vitro. 2018 Apr;48:121-127.
- [3]. Kondratskyi A1, et al.Identification of ML-9 as a lysosomotropic agent targeting autophagy and cell death.Cell Death Dis. 2014 Apr 24;5:e1193.
- Hidaka, H., et al.: J. Biol. Chem., 262, 16, 7796 (1987)
- [1]. Ito S, et al. ML-9, a myosin light chain kinase inhibitor, reduces intracellular Ca2+ concentration in guinea pig trachealis.Eur J Pharmacol. 2004 Feb 23;486(3):325-33.
- [1]. Ito S, et al. ML-9, a myosin light chain kinase inhibitor, reduces intracellular Ca2+ concentration in guinea pig trachealis.Eur J Pharmacol. 2004 Feb 23;486(3):325-33.
- [2]. Shaikh S, et al. The STIM1 inhibitor ML9 disrupts basal autophagy in cardiomyocytes by decreasing lysosome content.Toxicol In Vitro. 2018 Apr;48:121-127.
- [3]. Kondratskyi A1, et al.Identification of ML-9 as a lysosomotropic a
