1-((5-iodonaphthalen-1-yl)sulfonyl)-1,4-diazepane hydrochloride 1-(5-碘萘-1-磺酰基)-1H-六氢-1,4-二氮杂卓盐酸盐
CAS 110448-33-4 MFCD00065524
化学结构图
SMILES: Cl.O=S(=O)(C1C=CC=C2C(I)=CC=CC=12)N1CCCNCC1
化学属性
| Mol. Formula | C15H17IN2O2S · HCl |
|---|---|
| Mol. Weight | 452.74 |
别名和识别编码
| Chemical Name | 1-((5-iodonaphthalen-1-yl)sulfonyl)-1,4-diazepane hydrochloride |
|---|---|
| CAS Number | 110448-33-4 |
| Synonym | 1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride Hexahydro-1-[(5-iodo-1-naphthalenyl)sulfonyl]-1H-1,4-diazepine Monohydrochloride ML-7 |
| MDL Number | MFCD00065524 |
| PubChem Substance ID | 24278490 |
| Chemical Name Translation | 1-(5-碘萘-1-磺酰基)-1H-六氢-1,4-二氮杂卓盐酸盐 |
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分类
- {SNA} Bioactive Small Molecules, Biochemicals and Reagents,
- {SNA} Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Kinase/Phosphatase Biology, L to O, M, Myosin Light Chain Kinase, Myosin Light Chain Kinase (MLCK), P to Q, Protein Kinase Inhibitors, Protein kinase A, Protein kinase C, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 分子生物学, 生化试剂, 生物活性小分子, 磷酸化分析, 细胞信号转导和神经科学, 细胞生物学, 翻译后修饰, 蛋白质组学, 酶、抑制剂和底物
- I
产品应用
- A potent and selective inhibitor of myosin light chain kinase.
相关文献及参考
- Hidaka, H., et al.: J. Biol. Chem., 262, 7796 (1987)
- Makishima, M., et al. FEBS Lett. 287 , 175, (1991) 摘要
