CAS 523-50-2 MFCD00064930-Angelicin 异补骨脂素 TAO{mole}

Angelicin 异补骨脂素

CAS 523-50-2 MFCD00064930

化学结构图

SMILES: O=c1ccc2ccc3occc3c2o1

化学属性

Mol. Formula	C11H6O3
Mol. Weight	186
Density	1.389
Melting Point	138.0 to 142.0 deg-C
Boiling Point	104°C/4mmHg(lit.)

别名和识别编码

Chemical Name	Angelicin
MDL Number	MFCD00064930
CAS Number	523-50-2
Synonym	2-OXO-[2H]-FURO[2,3-H]-1-BENZOPYRAN 2-Oxo-(2H)-furo(2,3-h)-1-benzopyran 2h-furo(2,3-h)(1)benzopyran-2-one 2h-furo(2,3-h)-1-benzopyran-2-one 3-(4-hydroxy-5-benzofuranyl)-2-propenoicacidelta-lactone 3-(4-hydroxy-5-benzofuranyl)-2-propenoicacidgamma-lactone 4-hydroxy-5-benzofuranacrylicacidgamma-lactone ANGELICIN ANGELICINE hplc Angecin Angelicin Furo(5',4',7,8)coumarin ISOPSORALEN ISOPSORALENE Isopsoralen （Angelicin） NSC 404563 angecin angelicin furo(2,3-h)coumarin isopsoralen 异补骨脂素异补骨酯素异香柠檬烯
PubChem Substance ID	10658
Reaxys-RN	153970
EC Number	250-023-7
Beilstein Registry Number	153970
Chemical Name Translation	异补骨脂素
Wiswesser Line Notation	T B566 EO LVOJ
LabNetwork Molecule ID	LN00202465
InChI	InChI=1S/C11H6O3/c12-10-4-2-7-1-3-9-8(5-6-13-9)11(7)14-10/h1-6H

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

安全信息

WGK Germany3

GHS Symbol

Precautionary statements

P201 Obtain special instructions before use. 使用前获取专门指示。
P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P281 Use personal protective equipment as required. 使用所需的个人防护装备。
P301+P312
P301+P312+P330
P302+P350
P302+P352
P304+P312
P304+P340
P305+P351+P338
P305+P351+P338+P337+P313
P308+P313
P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
P322 Specific measures (see …on this label). 具体治疗（见本标签上的）。
P330 Rinse mouth. 漱口
P332+P313
P337+P313
P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
P403+P233
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Hazard statements

H302 Harmful if swallowed 吞食有害
H302+H312+H332
H312 Harmful in contact with skin 皮肤接触有害
H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛
H332 Harmful if inhaled 吸入有害
H335 May cause respiratory irritation 可能导致呼吸道刺激
H351 Suspected of causing cancer 怀疑致癌

RTECSLV0940000

Signal word

Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Hazard Codes Xn

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用

Storage condition -20°C 2-8°C -20

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 165 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - ataxia
   Behavioral - analgesia
REFERENCE :
   IJMRAQ Indian Journal of Medical Research.  (Indian Council of Medical
   Research, Ansari Nagar, New Delhi 110 029, India)  V.1-    1913-
   Volume(issue)/page/year: 63,833,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 254 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - ataxia
   Behavioral - analgesia
REFERENCE :
   IJMRAQ Indian Journal of Medical Research.  (Indian Council of Medical
   Research, Ansari Nagar, New Delhi 110 029, India)  V.1-    1913-
   Volume(issue)/page/year: 63,833,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 322 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - ataxia
   Behavioral - analgesia
REFERENCE :
   IJMRAQ Indian Journal of Medical Research.  (Indian Council of Medical
   Research, Ansari Nagar, New Delhi 110 029, India)  V.1-    1913-
   Volume(issue)/page/year: 63,833,1975

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 50 umol/L
REFERENCE :
   BUCABS Bulletin du Cancer.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.53-
   1966-  Volume(issue)/page/year: 67,245,1980

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 40 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 58,23,1978

TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 100 umol/L
REFERENCE :
   BUCABS Bulletin du Cancer.  (SPPIF, B.P.22, F-41353 Vineuil, France)  V.53-
   1966-  Volume(issue)/page/year: 67,245,1980

其他信息

MOL 文件:523-50-2.mol
上游原料:盐酸 --> 乙酸乙酯 --> 甲醇 --> 乙醚 --> 四氢呋喃 --> 石油醚 --> 硫酸镁 --> 氢氧化钾 --> 氯化钠 --> 碳酸氢钠 --> 苯 --> 氢化钠 --> 二甲苯 --> 甲酸乙酯 --> 氯乙醛 --> 1,3-环己二酮 --> 氢化钾 --> 2,3-二氯-5,6-二氰基-1,4-苯醌 --> 乙氧甲酰基亚甲基三苯基膦
Sigma Aldrich:523-50-2(sigmaaldrich)