Choline Glycerophosphate 甘油磷酸胆碱
CAS 28319-77-9 MFCD00063544
化学结构图
SMILES: C[N+](C)(C)CCOP([O-])(=O)OC[C@H](O)CO
化学属性
| Mol. Formula | C8H20NO6P |
|---|---|
| Mol. Weight | 257.22 |
别名和识别编码
| Chemical Name | Choline Glycerophosphate |
|---|---|
| CAS Number | 28319-77-9 |
| Synonym | ######## Choline alfoscerate Choline, hydroxide, 2,3-dihydroxypropyl hydrogen phosphate, inner salt, |
| MDL Number | MFCD00063544 |
| PubChem Substance ID | 24895204 |
| EC Number | 248-962-2 |
| Chemical Name Translation | 甘油磷酸胆碱 |
| Beilstein Registry Number | 6062450 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Activity, Activity Other, Enzyme Substrates, 代谢组学, 代谢通路, 生化试剂, 磷酸甘油酯代谢, 细胞生物学, 酶、抑制剂和底物
- Activity, Activity Other, Biochemicals and Reagents, Enzyme Substrates, Enzymes, Inhibitors, and Substrates, Glycerophospholipid Metabolism, Metabolic Pathways, Metabolomics
- {SNA} Activity, Activity Other, Biochemicals and Reagents, Enzyme Substrates, Enzymes, Inhibitors, and Substrates, Glycerophospholipid Metabolism, Metabolic Pathways, Metabolomics
产品应用
- sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a phospholipid; precursor in choline biosynthesis. sn-Glycero-3-phosphocholine is an intermediate in catabolic pathway of phosphatidylcholine. sn-G
相关文献及参考
- [2]. Traini E, et al. Choline alphoscerate (alpha-glyceryl-phosphoryl-choline) an old choline- containing phospholipidwith a still interesting profile as cognition enhancing agent. Curr Alzheimer Res. 2013 Dec;10(10):1070-9.
- [3]. Lee SH, et al. Late treatment with choline alfoscerate (l-alpha glycerylphosphorylcholine, α-GPC) increases hippocampal neurogenesis and provides protection against seizure-induced neuronal death and cognitive impairment. Brain Res. 2017 Jan 1;1654(Pt A):66-76.
- Aleppo, G., et al., Chronic L-alpha-glyceryl-phosphoryl-choline increases inositol phosphate formation in brain slices and neuronal cultures. Pharmacol. Toxicol. 74 , 95, (1994) 摘要
- Frattola, L., et al.: Curr. Ther. Res., 49, 683 (1991),
- Olson, D., et al.: Science, 270, 1967 (1995),
- Schmidt, G., et al.: J. Biol. Chem., 161, 523 (1945),
- [1]. Traini E, et al. Choline alphoscerate (alpha-glyceryl-phosphoryl-choline) an old choline- containing phosphol
安全信息
GHS Symbol
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >650 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #93-32553
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >13 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #93-32553
