CAS 53-60-1 MFCD00058535-Promazine Hydrochloride 盐酸丙嗪 TAO{mole}

Promazine Hydrochloride 盐酸丙嗪

CAS 53-60-1 MFCD00058535

化学结构图

SMILES: CN(C)CCCN1c2ccccc2Sc2ccccc21.Cl

化学属性

Mol. Formula	C17H20N2S · HCl
Mol. Weight	320.88

别名和识别编码

Chemical Name	Promazine Hydrochloride
CAS Number	53-60-1
Synonym	10-(3-(dimethylamino)propyl 10-(3-(dimethylamino)propyl)-phenothiazinmonohydrochloride 10-(3-(dimethylamino)propyl)phenothiazinemonohydrochloride 10-(gamma-dimethylamino-n-propyl)phenothiazinehydrochloride 10-[3-(DIMETHYLAMINO)PROPYL]-PHENOTHIAZ Chlorowodorek promazyny Esparinal Hydrochloride, Promazine Liranol Megaphen N,N-Dimethyl- N,N-二甲基-10H-吩噻嗪-10-丙胺盐酸盐 N-(3-(Dimethylamino)propyl)phenothiazine hydrochloride PROMAZINE HCL PROMAZINE HYDROCHLORIDE Phenothiazine, 10-(3-(dimethylamino)propyl)-, hydrochloride Promazine Promazine Hydrochloride Promazine hydrochloride Protactyl RP 4560 Sinophenin Sparine chlorowodorekpromazyny component of K
MDL Number	MFCD00058535
PubChem Substance ID	5887
Beilstein Registry Number	3753230
EC Number	200-179-7
Chemical Name Translation	盐酸丙嗪
Wiswesser Line Notation	T C666 BN ISJ B3N1&1 &GH
LabNetwork Molecule ID	LN00193237
InChI	InChI=1S/C17H20N2S.ClH/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)20-17-11-6-4-9-15(17)19;/h3-6,8-11H,7,12-13H2,1-2H3;1H

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产品应用

Antipsychotic. Tranquilizer.

安全信息

WGK Germany3

GHS Symbol

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P301+P312
P301+P312+P330
P302+P352
P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
P330 Rinse mouth. 漱口
P333+P313
P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Hazard statements

H302 Harmful if swallowed 吞食有害
H317 May cause an allergic skin reaction 可能导致皮肤过敏

RTECSSO8575000

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Signal word Warning

Hazard Codes Xn

Safety Statements

S36 Wear suitable protective clothing 穿戴适当的防护服；

Risk Statements

R22 Harmful if swallowed 吞咽有害
R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应

Storage condition 2-8°C 储存温度2-8°C

{h

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAZMAE Fortschritte der Arzneimittelforschung.  Progress in Drug Research.
   (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way,
   Secaucus, NJ 07094)  V.1-    1959-  Volume(issu

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 4400 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes,
   C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973
   Volume(issue)/page/year: -,-,1965

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 356 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 54,295,1965

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC

其他信息

Sigma Aldrich:53-60-1(sigmaaldrich)
MOL 文件:53-60-1.mol