CAS 55-16-3 MFCD00058096-Scopolamine Hydrochloride 盐酸东莨菪碱 TAO{mole}

Scopolamine Hydrochloride 盐酸东莨菪碱

CAS 55-16-3 MFCD00058096

化学结构图

SMILES: Cl.CN1[C@@H]2C[C@H](C[C@H]1[C@@H]1O[C@@H]12)OC(=O)[C@@H](CO)C1C=CC=CC=1 |&1:3,5,7,8,10,14|

化学属性

Mol. Formula	C17H21NO4.ClH
Mol. Weight	339.85
Flash Point	77 °C
Solubility	Soluble in water: 50 mg/mL
Appearance	powder

别名和识别编码

Chemical Name	Scopolamine Hydrochloride
CAS Number	55-16-3
MDL Number	MFCD00058096
Synonym	Scopolamine, hydrochloride 5-alpha-h-tropan-3-alpha-ol,6-beta,7-beta-epoxy-1-alpha-(-)-tropate(est 莨菪碱天仙子碱盐酸盐莨菪胺 ScopolamineSeries (-)-盐酸东莨菪碱 Hyoscine hydrochloride (-)-莨菪胺盐酸盐 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, 6-beta,7-beta-epoxy-, (-)-tropate HYOSCINE HYDROCHLORIDE )-Scopolamine hydrochloride chlorhydratedescopolamine SCOPINE TROPATE HYDROCHLORIDE Scopine tropate (-)-东莨菪碱盐酸盐; 天仙子碱盐酸盐; 莨菪胺 (-)-SCOPOLAMINE HYDROCHLORIDE (- (-)-Scopolaminhydrochlorid 0(sup2,4))non-7-ylester,hydrochloride,(7(s)-(1-alpha,2-beta,4-beta,5-alpha er),hcl, SCOPINE TROPATE Chlorhydrate de scopolamine HYPACONITINE(P) (-)-东莨菪碱盐酸盐 Hyoscine hydrochloride, Scopine tropate SCOPOLAMINE HYDROCHLORIDE 盐酸(-)-莨菪胺
Beilstein Registry Number	4168778
EC Number	200-225-6
PubChem Substance ID	24899457
Chemical Name Translation	盐酸东莨菪碱
Wiswesser Line Notation	T C356 A AN DOTJ A1 HOVYR&1Q &GH
LabNetwork Molecule ID	LN02126871

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

竞争性非选择性蕈毒性乙酰胆碱拮抗剂。常在实验动物上进行莨菪碱诱导健忘症实验。

安全信息

RTECSCY1634501

GHS Symbol

Precautionary statements

P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P301+P310
P284 Wear respiratory protection.? 佩戴呼吸保护装置。
P302+P350
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。

Hazard statements

H330 Fatal if inhaled 吸入致命
H310 Fatal in contact with skin 皮肤接触致命
H300 Fatal if swallowed 吞食致命
H300+H310+H330

WGK Germany3

Signal word Danger

Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Hazard Codes T+

Safety Statements

S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S25 Avoid contact with eyes 避免眼睛接触；
S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；

Risk Statements

R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有剧毒

UN Number 1544 UN 1544 6.1/PG 3

Storage condition 储存温度-20°C

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1275 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SMWOAS Schweizerische Medizinische Wochenschrift.  (Schwabe & Co.,
   Steintorst 13, 4010 Basel, Switzerland)  V.50-    1920-
   Volume(issue)/page/year: 88,713,1958

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 104 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - parasympatholytic
REFERENCE :
   ATXKA8 Archiv fuer Toxikologie.  (Berlin, Fed. Rep. Ger.)  V.15-31, 1954-74.
    For publisher information, see ARTODN.  Volume(issue)/page/year: 29,39,1972

其他信息

急救治疗:发现中毒症状状，催吐或吞入活性炭，必要时送医院诊治。
类别:有毒物质
灭火剂:水, 二氧化碳, 干粉, 砂土
毒性分级:中毒
注意事项:[1]按亩用剂量量取药液，兑水50g充分搅拌，均匀喷雾。 [2]本品不易与其它农药混配使用。 [3]本品应存放于阴凉干燥处，防止曝晒。 [4]若误服或出现中毒症状，送医院诊治
用途一:竞争性非选择性蕈毒性乙酰胆碱拮抗剂。常在实验动物上进行莨菪碱诱导健忘症实验。
MOL 文件:55-16-3.mol
Sigma Aldrich:55-16-3(sigmaaldrich)
color:white
急性毒性:口服-小鼠 LD50: 1275 毫克/公斤; 腹腔-小鼠 LD50: 104 毫克/公斤
F:3-8
储运特性:库房低温, 通风, 干燥
(-)-Scopolamine hydrochloride is a competitive nonselective mAChR M antagonist. This compound blocks the binding of the acetylcholine ligand and prevents the opening of ion channels.
可燃性危险特性:可燃, 燃烧时分解有毒氮氧化物, 氯化物气体