CAS 18694-40-1 MFCD00057351-Epirizole 依匹唑 TAO{mole}

Epirizole 依匹唑

CAS 18694-40-1 MFCD00057351

化学结构图

SMILES: CC1C=C(OC)N(N=1)C1N=C(C=C(C)N=1)OC

化学属性

Mol. Formula	C11H14N4O2
Mol. Weight	234.29

别名和识别编码

Chemical Name	Epirizole
EC Number	242-507-1
Synonym	2-(3-Methyl-5-methoxy-1-pyrazolyl)-4-methoxy-6-methylpyrimidine Epirizole 2-(5-Methoxy-3-methyl-1-pyrazinyl)-4-methoxy-6-methyl-pyrimidine 2-(3-Methoxy-5-methylpyrazol-2-yl)-4-methoxy-6-methylpyrimidine Mepirizole Mebron DA-398 甲嘧啶唑 4-Methoxy-2-(5-methoxy-3-methylpyrazol-1-yl)-6-methylpyrimidin 1-(4-Methoxy-6-methyl-2-pyrimidinyl)-3-methyl-5-methoxypyrazole Mepirizol 4-Methoxy-2-(5-methoxy-3-methyl-1H-pyrazol-1-yl)-6-methylpyrimidine
CAS Number	18694-40-1
MDL Number	MFCD00057351
PubChem Substance ID	24897309
Wiswesser Line Notation	T6N CNJ B- AT5NNJ C1 EO1& DO1 F1
Beilstein Registry Number	0751084
Chemical Name Translation	依匹唑

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

安全信息

Hazard Codes Xn

Safety Statements

S36 Wear suitable protective clothing 穿戴适当的防护服；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害

RTECSUV9290000

GHS Symbol

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P305+P351+P338

Hazard statements

H332 Harmful if inhaled 吸入有害
H315 Causes skin irritation 会刺激皮肤
H302 Harmful if swallowed 吞食有害
H312 Harmful in contact with skin 皮肤接触有害
H335 May cause respiratory irritation 可能导致呼吸道刺激
H319 Causes serious eye irritation 严重刺激眼睛

WGK Germany3

Signal word Warning

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 550 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMGZAI Japan Medical Gazette.  (Tokyo, Japan)  V.1-18(?), 1964-81.
   Discontinued.  Volume(issue)/page/year: 7(9),5,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 550 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   IYKEDH Iyakuhin Kenkyu.  Study of Medical Supplies.  (Nippon Koteisho
   Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan)  V.1- 1970- 
   Volume(issue)/page/year: 8,494,1977

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 214 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMGZAI Japan Medical Gazette.  (Tokyo, Japan)  V.1-18(?), 1964-81.
   Discontinued.  Volume(issue)/page/year: 7(9),5,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent

TYPE OF TEST            : LD50 - Lethal dose, 50 per

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 540 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 16,1011,1978