CAS 64092-48-4 MFCD00057223-Sodium 2-(5-(4-Chlorobenzoyl)-1,4-Dimethyl-1H-Pyrrol-2-Yl)Acetate 2-(5-(4-氯苯甲酰基)-1,4-二甲基-1H-吡咯-2-基)乙酸钠 TAO{mole}

Sodium 2-(5-(4-Chlorobenzoyl)-1,4-Dimethyl-1H-Pyrrol-2-Yl)Acetate 2-(5-(4-氯苯甲酰基)-1,4-二甲基-1H-吡咯-2-基)乙酸钠

CAS 64092-48-4 MFCD00057223

化学结构图

SMILES: [Na+].CC1C=C(CC([O-])=O)N(C)C=1C(=O)C1C=CC(Cl)=CC=1

化学属性

Mol. Formula	C15H13ClNO3Na
Mol. Weight	313.71

别名和识别编码

Chemical Name	Sodium 2-(5-(4-Chlorobenzoyl)-1,4-Dimethyl-1H-Pyrrol-2-Yl)Acetate
CAS Number	64092-48-4
Synonym	5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic Acid Sodium Salt 5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid sodium salt 5-(p-Chlorobenzoyl)-1,4-dimethylpyrrole-2-acetic acid sodium-potassium salt McN 2783-21-98 Sodium Zomepirac Zomax Zomepirac Sodium Zomepirac Sodium Salt Zomepirac sodium salt
MDL Number	MFCD00057223
PubChem Substance ID	24902176
EC Number	264-669-2
Wiswesser Line Notation	T5NJ A1 BVR DG& C1 E1VO &-NA- &QH 2
Chemical Name Translation	2-(5-(4-氯苯甲酰基)-1,4-二甲基-1H-吡咯-2-基)乙酸钠

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产品应用

Zomepirac is an analgesic, anti-inflammatory drug.

安全信息

WGK Germany3

GHS Symbol

Precautionary statements

P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P301+P310
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。

Signal word Danger

Hazard statements

H331 Toxic if inhaled 吸入中毒
H311 Toxic in contact with skin 皮肤接触中毒
H300 Fatal if swallowed 吞食致命

RTECSUX9277000

Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Safety Statements

S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S22 Do not breathe dust 不要吸入粉尘；

Hazard Codes T

Risk Statements

R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 27 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRUGAY Drugs. International Journal of Current Therapeutics and Applied
   Pharmacology Reviews.  (ADIS Press International Inc., Suite B-30, Oxford
   Ct. Business Center, 582 Middletown Blvd., Langhorne, PA 19047)  V.1- 1971- 
   Volume(issue)/page/year: 23,250,1982

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 70 mg/kg/10D-I
TOXIC EFFECTS :
   Gastrointestinal - nausea or vomiting
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
   Immunological Including Allergic - anaphylaxis
REFERENCE :
   AJMEAZ American Journal of Medi

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 16 mg/kg/2D-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
REFERENCE :
   AIMDAP Archives of Internal Medicine.  (AMA, 535 N. Dearborn St., Chicago,
   IL 60610)  V.1-    1908-  Volume(issue)/page/year: 143,1171,1983

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 117 mg/kg
TOXIC EFFECTS :
   Behavioral - coma
   Cardiac - pulse rate increase, without fall in BP
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   JATOD3 Journal of Analytical Toxicology.  (Preston Pub. Inc., POB 48312,
   Niles, IL 60648) V.1-    1977-  Volume(issue)/page/year: 7,223,1983