Fenbufen 芬布芬

CAS 36330-85-5 MFCD00056701

化学结构图

36330-85-5
SMILES: OC(=O)CCC(=O)C1=CC2C3C=CC=C4C=CC=C(C4=3)C=2C=C1

化学属性

Mol. FormulaC16H14O3
Mol. Weight254
Melting Point184-187 °C (lit.)
TSCANo

别名和识别编码

Chemical NameFenbufen
CAS Number36330-85-5
Synonym Butyric acid 4-(4-biphenyl 4-(4-Biphenylyl)-4-oxobutyric acid FENBUFEN 夫洛梯隆 CL 82204 3-(4-Biphenylylcarbonyl)propionic acid 3-(4-PHENYLBENZOYL)PROPIONIC ACID 4-(fluoranthen-8-yl)-4-oxobutyric acid Zanchol Diphenyl-4-gamma-oxo-gamma-butyric acid Cinopal 4-(4-BIPHENYL)-4-OXOBUTYRIC ACID g-Fluoranthen-8-yl-g-oxybutyric acid γ-Oxo-8-fluoranthenebutyric acid 4-Fluoranthen-8-yl-4-oxobutanoic acid ?-Oxo[1,1'-biphenyl]-4-butanoic Acid GAMMA-OXO(1,1'-BIPHENYL)-BUTANOIC ACID florantyrone Propionic acid, 3-(4-biphenylylcarbonyl)- 4-(4-BIPHENYLYL)-4-OXOBUTYRIC ACID Fenbufen Bufemid γ-氧-(1,1′-联苯)-4-丁酸 gamma-Oxo(1,1'-biphenyl)-4-butanoic acid
MDL NumberMFCD00056701
PubChem Substance ID329758009
EC Number252-979-0
Chemical Name Translation芬布芬
Wiswesser Line NotationQV2VR DR
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分类

  • Pharmaceuticals
  • {SA} Building Blocks, C13 to C42+, Carbonyl Compounds, Carboxylic Acids, Chemical Synthesis, Organic Building Blocks
  • Aromatics
  • Intermediates & Fine Chemicals
  • {SNA} Building Blocks, C13 to C42+, Carbonyl Compounds, Carboxylic Acids, Chemical Synthesis, Organic Building Blocks

产品应用

  • Anti-inflammatory.

相关文献及参考

  • Becker, A., et al.: J. Int. Med. Res., 8, 333 (1980),
  • Child, R.G., et al.: Arzneim.-Forsch., 30, 695 (1980),

安全信息

RTECSDV1761000
GHS Symbol
Precautionary statements
  • P301+P310
Signal word Danger
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
WGK Germany3
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S20 When using do not eat or drink 使用时,不得进食,饮水;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
Packing GroupIII
UN Number UN 2811 6.1/PG 3 UN2811
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒
Hazard Codes T
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 2314 mg/kg/26W-I
TOXIC EFFECTS :
   Blood - aplastic anemia
REFERENCE :
   BJRHDF British Journal of Rheumatology.  (Bailliere Tindall, 33 The Avenue,
   Eastborn BN21 3UN, UK)  Volume(issue)/page/year: 33,389,1994

其他信息

  • MOL 文件:519-95-9.mol
  • MSDS 信息:Florantyrone(519-95-9).msds

系列性分类


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