CAS 51-57-0 MFCD00056130-(+)-Methamphetamine hydrochloride solution S-(+)-Methamphetamine TAO{mole}

(+)-Methamphetamine hydrochloride solution S-(+)-Methamphetamine

CAS 51-57-0 MFCD00056130

化学结构图

SMILES: CN[C@@H](C)Cc1ccccc1.Cl

化学属性

Mol. Formula	C10H15N.ClH
Mol. Weight	185.72

别名和识别编码

Chemical Name	Hydrochloride
CAS Number	51-57-0
Synonym	{uni_hamburg} Philopon Drinalfa d-Desoxyephedrine hydrochloride Desoxyfed Dextim Methylisomyn Destim Gerovit Doxyfed (+)-Methamphetamine chloride Adipex Norodin hydrochloride d-Methylamphetamine hydrochloride Methamphetaminium chloride Soxysympamine (S)-N, α-dimethylbenzeneethanamine hydrochloride Efroxine Deofed Tonedron Pervitin N-Methylamphetamine hydrochloride Eufodrinal Syndrox Desoxyn Desyphed d-N-Methyl-beta-phenylisopropylamine hydrochloride Methylamphetamine hydrochloride Dexoval (+)-甲基苯丙胺盐酸盐溶液 d-Deoxyephedrine hydrochloride (?S)- (+)-Methamphetamine hydrochloride (S)-N, a-dimethylbenzene ethanamine hydrochloride methamphetamine hydrochloride Benzeneethanamine, N,alpha-dimethyl-, hydrochloride, (S)- d-Methamphetamine hydrochloride Isophen
PubChem Substance ID	24896988
MDL Number	MFCD00056130
EC Number	200-106-9
Wiswesser Line Notation	1MY1R &GH
Chemical Name Translation	S-(+)-Methamphetamine

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分类

Amines
Aromatics
Pharmaceuticals
Intermediates & Fine Chemicals,
{uni_hamburg} no charge; carbocycle; aromatic; 6RingOnly; 6ring; chiral; 2fragments; ionic
{SA} β-Glucuronidase, β-Glucuronidase Drug Analysis Bundle, Alphabetic, Amphetamine, Analytical Standards, Analytical and Industrial Enzymes, Analytical/Chromatography, Biochemicals and Reagents, Chemical Structure, Chromatography, Drug standards, Drugs & Metabolites, Drugs of Abuse, Enzymes, Inhibitors, and Substrates, Forensic and Veterinary Standards, M, META - METH, Solutions
{SNA} β-Glucuronidase, β-Glucuronidase Drug Analysis Bundle, Alphabetical Index of Analytical Standards, Amphetamine, Analytical Standards,

产品应用

A CNS stimulant. Anorexic. In attention deficit disorder with hyperactivity.

安全信息

GHS Symbol

WGK Germany1

Hazard statements

H370 Causes damage to organs 导致器官损伤
H331 Toxic if inhaled 吸入中毒
H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
H301 Toxic if swallowed 吞食有毒
H311 Toxic in contact with skin 皮肤接触中毒

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US)

Precautionary statements

P301+P310
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。

Signal word Danger

RTECSSH5455000

Hazard Codes F,T

Safety Statements

S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；

Risk Statements

R11 Highly flammable 非常易燃
R39/23/24/25 Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed 毒性：吸入，皮肤接触和吞食都会产生十分严重的不可逆危险
R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒

Restrict 精神药品

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 400 mg/kg
                          female 1-21 day(s) after conception
                          lactating female 19 day(s) post-birth
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Reproductive - Tumorigenic effects - transplacental tumorigenesis
REFERENCE :
   EAGRDS Experimental Aging Research.  (Beech Hill Pub. Co., POB 136,
   Southwest Harbor, ME 04679) V.1-    1975-  Volume(issue)/page/year:
   5,509,1979

{hazard_com

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 15 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,346,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10930 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 253,466,1990

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#02170

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7560 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 87,214,1946

TYPE OF TEST            : LD

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 792 mg/kg
SEX/DURATION            : male 4 week(s) pre-mating
                          female 4 week(s) pre-mating  - 3 week(s) post-birth
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - biochemical and metabolic
REFERENCE :
   JONRA9 Journal of Neurochemistry.  (Raven Press, 1185 Ave. of the Americas,
   New York, NY 10036) V.1-    1956-  Volume(issue)/page/year: 20,625,1973

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 19 mg/kg
SEX/DURATION            : female 8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - other developmental
   abnormalities
REFERENCE :
   NHOZAX Nippon Hoigaku Zasshi.  Japanese Journal of Legal Medicine.  (Nippon
   Hoi Gakkai, c/o Tokyo Daigaku Igakubu Hoigaku Kyoshitsu, 7-3-1, Hongo,
   Bunkyo-ku, Tokyo 113, Japan)  V.1-    1944-  Volume(issue)/page/year:
   46,126,1992

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperito

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 17 mg/kg
SEX/DURATION            : female 8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - Central Nervous System
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   NHOZAX Nippon Hoigaku Zasshi.  Japanese Journal of Legal Medicine.  (Nippon
   Hoi Gakkai, c/o Tokyo Daigaku Igakubu Hoigaku Kyoshitsu, 7-3-1, Hongo,
   Bunkyo-ku, Tokyo 113, Japan)  V.1-    1944-  Volume(issue)/page/year:
   46,126,1992