1-((2R,4S,5R)-4-Fluoro-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)-5-Methylpyrimidine-2,4(1H,3H)-Dione 3’-脱氧-3-氟胸苷

CAS 25526-93-6 MFCD00056058

化学结构图

25526-93-6
SMILES: CC1=CN([C@H]2C[C@H](F)[C@@H](CO)O2)C(=O)NC1=O

化学属性

Mol. FormulaC10H13FN2O4
Mol. Weight244
Melting Point176-178

别名和识别编码

Chemical Name1-((2R,4S,5R)-4-Fluoro-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)-5-Methylpyrimidine-2,4(1H,3H)-Dione
CAS Number25526-93-6
Synonym 3'-Fluorothymidine 3′-脱氧-3′-氟胸苷 Alovudine
MDL NumberMFCD00056058
PubChem Substance ID24862180
Chemical Name Translation3’-脱氧-3-氟胸苷
Wiswesser Line NotationT6NVMVJ E1 A- ET5OTJ B1Q CF
Beilstein Registry Number0754299
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分类

  • {SNA} Bioactive Small Molecules, Cell Biology, Chemical Biology, Chemical Synthesis, D-DIF, Nucleoside Chemistry, Nucleosides
  • Bases & Related Reagents
  • {SNA} Chemical Biology, Chemical Synthesis, Nucleobase, Nucleoside and Nucleotide Derivatives, Nucleoside Chemistry
  • Nucleotides
  • Carbohydrates & Derivatives

产品应用

  • An antiviral agent.

相关文献及参考

  • Hoffman, B., et al.: J. Med. Chem., 43, 4151

安全信息

WGK Germany3
RTECSXP2073000
GHS Symbol
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - mouse Ascites tumor
DOSE/DURATION           : 10 umol/L
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   32,178,1977

系列性分类


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