CAS 299-86-5 MFCD00055452-Crufomate 育畜磷 TAO{mole}

Crufomate 育畜磷

CAS 299-86-5 MFCD00055452

化学结构图

SMILES: CNP(=O)(OC)Oc1ccc(C(C)(C)C)cc1Cl

化学属性

Mol. Formula	C12H19ClNO3P
Mol. Weight	291.74
Density	1.176

别名和识别编码

Chemical Name	Crufomate
CAS Number	299-86-5
Synonym	######## (RS)-4-tert-Butyl-2-chlorophenyl methyl methylphosphoramidate Amidofos Amidophos NSC 253463 Ruelene 2-Chlor-4-(1,1-dimethylethyl)phenylmethylmethylphosphoramidat 2-chloro-4-(1,1-dimethylethyl)phenyl methyl methylphospho 2-chloro-4-(1,1-dimethylethyl)phenylmethyl methylphosphoramidate 4-tert-But 4-tert-Butyl-2-chlorophenyl methyl methylphosphoroamidate 4-tert-Butyl-2-chlorphenyl(methyl)methylamidophosphat 4-tert-butyl-2-chlorophenyl methyl methylphosphoramidate 4-t-Butyl-2-chlorophenyl methyl methylphosphoramidate o-(4-tert-Butyl-2-chlor-phenyl)-O-methyl-phosphorsäure-N-methylamid Amidofos Amidopho Crufomate A Cruformate Dowco 132 ENT 25,602-X Ent 25,602-x M-1261
MDL Number	MFCD00055452
Beilstein Registry Number	2133258
EC Number	206-083-1
Chemical Name Translation	育畜磷
Wiswesser Line Notation	1X1&1&R CG DOPO&O1&M1
PubChem Substance ID	9300
InChI	InChI=1S/C12H19ClNO3P/c1-12(2,3)9-6-7-11(10(13)8-9)17-18(15,14-4)16-5/h6-8H,1-5H3,(H,14,15)

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产品应用

Crufomate is an organophosphate pesticide. Crufomate is an anthelmintic that functions as a potent inhibitor of an acetylcholinesterase in the anterior end of the worms. Crufomate is also used to comb

安全信息

GHS Symbol

Precautionary statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P273 Avoid release to the environment. 避免释放到环境中。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P301+P312
P302+P352
P304+P340
P305+P351+P338
P309+P311
P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
P322 Specific measures (see …on this label). 具体治疗（见本标签上的）。
P330 Rinse mouth. 漱口
P332+P313
P337+P313
P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
P403+P233
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Hazard statements

H302+H312
H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。

WGK Germany3

Signal word Warning

Safety Statements

S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；

Hazard Codes Xn,N

Risk Statements

R21/22 Harmful in contact with skin and if swallowed 皮肤接触和不慎吞咽有害
R50/53

RTECSTB3850000

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   STCC** Stauffer Chemical Co., Product Safety Information Sheets.  (Stauffer
   Chemical Co., Agricultural Chemical Div., Westport, CT 06880)

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 460 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   14,515,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   SPEADM Special Publication of the Entomological Society of America.  (4603
   Calvert Rd., College Park, MD 20740)  Volume(issue)/page/year: 78-1,37,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   21,315,1972

TYPE OF TEST            : LCL

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 100 mg/kg
SEX/DURATION            : female 2 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - mating performance (e.g. # sperm positive females
   per # females mated; # copulations per # estrus cycles)
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   JPFCD2 Journal of Environmental Science and Health, Part B: Pesticides, Food
   Contaminants, and Agricultural Wastes.  (Marcel Dekker, 270 Madison Ave.,
   New York, NY 10016)  V.B11-    1976-  Volume(issue)/page/year: 13,169,1978

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 100 mg/kg
SEX/DURATION            : female 2 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - parturition
   Reproductive - Effects on Newborn - weaning or lactation index (e.g., #
   alive at weaning per # alive at day 4)
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   JPFCD2 Journal of Environmental Science and Health, Part B: Pesticides, Food
   Contaminants, and Agricultural Wastes.  (Marcel Dekker, 270 Madison Ave.,
   New York, NY 10016)  V.B11-    1976-  Volume(issue)/page/year: 16,141,1981

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 200 mg/kg
SEX/DURATION            : female 2 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - live birth index (measured after birth)
REFERENCE :
   JPFCD