6-Maleimidohexanoic acid 6-(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)己酸
CAS 55750-53-3 MFCD00043140
化学结构图
SMILES: O=C(O)CCCCCN1C(=O)C=CC1=O
化学属性
| Mol. Formula | C10H13NO4 |
|---|---|
| Mol. Weight | 211 |
| Melting Point | 86.0 to 91.0 deg-C |
| TSCA | No |
别名和识别编码
| Chemical Name | 6-Maleimidohexanoic acid |
|---|---|
| CAS Number | 55750-53-3 |
| Alfabeta Name | MALEIMIDOHEXANOICACID 6- |
| MDL Number | MFCD00043140 |
| Synonym | ?-Male Maleimidocaproic acid 6-Maleimidocaproic acid 6-Maleimide hexanoic acid 6-Maleimidocaproic acid, N-Maleoyl-6-aminocaproic acid, N-(5-Carboxypentyl)maleimide 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic acid 6-Maleimide hexanoic acid 6-Maleimidocaproic acid N-Maleoyl-6-aminocaproic acid MCA Maleimidocaproic acid N-(5-Carboxypentyl)maleimide 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoic Acid N-(5-Carboxy-n-pentyl)maleimide N-(5-Carboxypentyl)maleimide 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic acid 6-Maleimidohexanoic Acid |
| Beilstein Registry Number | 1532405 |
| PubChem Substance ID | 160871405 |
| Chemical Name Translation | 6-(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)己酸 |
| Reaxys-RN | 1532405 |
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分类
- {SNA} Asymmetric Synthesis, Carboxylic Acids, Chemical Synthesis, Chiral Building Blocks, Organic Building Blocks
- MTS & Sulfhydryl Active Reagents
- {SNA} Curing Agents for Epoxides, Polymer Additives, Polymer Science, 材料科学
- {SA} Crosslinking Agents and Additives for Epoxides, Materials Science, Polymer Additives, Polymer Science
- Cross Linking Reagents
- Maleimide Derivatives
产品应用
- A sulfhydryl reactive heterobifunctional crosslinking reagent. Widely used probe for introducing maleimides groups into biomolecules. A probe for thiol groups in proteins.
相关文献及参考
- Griffith, D.G., et al.: FEBS Lett., 134, 261 (1981)
- D.G. Griffith FEBS Lett. 134 , 261, (1981) 摘要
- O. Keller, J. Rudinger Helv. Chim. Acta 58 , 531, (1975) 摘要
- Beil. 21 ,V,10,30
安全信息
- S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S37 Wear suitable gloves 戴适当手套；
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P352+P332+P313+P362+P364
- P305+P351+P338
- P305+P351+P338+P337+P313
- H315 Causes skin irritation 会刺激皮肤
- H318 Causes serious eye damage 严重伤害眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
