Aldicarb 涕灭威

CAS 116-06-3 MFCD00041807

化学结构图

116-06-3
SMILES: CNC(=O)ON=CC(C)(C)SC

化学属性

Mol. FormulaC7H14N2O2S
Mol. Weight190.29
Flash Point>100 ºC
Solubility微溶于水,溶于丙酮、苯、四氯化碳。
Density1.0
Boiling Point1.1950
Melting Point98-100°C
Stability对光线敏感

别名和识别编码

Chemical NamePropionaldehyde, 2-methyl-2-(methylthio)-,O-(methylcarbamoyl)oxime
CAS Number116-06-3
Synonym 2-METHYL-2-( 2-Methyl-2(methylthio)propanal-o-[ 2-Methyl-2-(methylthio)propanal O-[(Methylamino)carbonyl]oxime 2-Methyl-2-(methylthio)propanal, O-((methylamino)carbonyl)oxi 2-Methyl-2-(methylthio)propionaldehyd-O-methylcarbamoyl-oxim 2-Methyl-2-(methylthio)propionaldehyde O-( 2-Methyl-2-(methylthio)propionaldehyde O-(Methylcarbamoyl)oxime 2-Methyl-2-methylthio-propionaldehyd-O-(N-methyl-carbamoyl)-oxim 2-Methyl-2-methylthio-propionaldehyd-O-(N-methyl-carbamoyl)-oxime 2-m 2-methyl-2-(methylthio)-propanao-((methy 2-methyl-2-(methylthio)-propanao-[(methylamino)carbonyl]oxime 2-methyl-2-(methylthio)-propionaldehydo-(methylcarbamoyl)oxime 2-methyl-2-(methylthio)-propionaldehydo-(methylcarbamoyl)oxime[qr] 2-methyl-2-(methylthio)propanal O-((methylamino)carbonyl)oxime {Chemicalb
PubChem Substance ID9570071
EC Number204-123-2
Beilstein Registry Number2209304
MDL NumberMFCD00041807
Chemical Name Translation涕灭威
Wiswesser Line Notation1SX1&1&1UNOVM1
InChIInChI=1S/C7H14N2O2S/c1-7(2,12-4)5-9-11-6(10)8-3/h5H,1-4H3,(H,8,10)/b9-5+
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分类

  • A, A-B, AA to AL, Acaricides, Alpha sort, Alphabetic, Analytical Standards, Analytical/Chromatography, Carbamates, Chromatography, EPA, Endocrine Disruptors (Draft), Environmental Standards, Insecticides, Method Specific, Nematicides, Pesticides, Pesticides & Metabolites
  • {uni_hamburg} no charge; carbamate; sulfide; 1fragment
  • {SNA} A, A-B, AA to AL, Acaricides, All alphabetically sorted, Alphabetical Index of Analytical Standards, Analytical Standards,

产品应用

  • 涕灭威是内吸性广谱杀虫螨剂,还可兼治线虫,主要作土壤处理,用来杀灭地下害虫,亦可由作物根部内吸,防治地上部分的多种害虫,如蓟马、蚜虫、叶蝉、粉虱、蝽象、红蜘蛛、潜叶蝇、甲虫。适用于棉花、花生、马铃薯、甜菜、甘薯、大豆、甘蔗、花卉、柑桔等多种作物。该品残效长,最长可达84d。因该品剧毒,只能以颗粒剂形式使用。规格有2%,5%,10%,15%颗粒剂。以颗粒剂形式小心施用于土壤还是安全的,而且药效好,在许多国家广泛使用,在氨基甲酸酯类杀剂中属于大吨位品种。
  • 校准仪器和装置;评价方法;工作标准;质量保证/质量控制;其他。

相关文献及参考

  • Ashby, J., et al.: Environ. Mutagen., 7, 919 (1985),
  • Kazius, J., et al.: J. Med. Chem., 48, 312 (2005),
  • Short: EINECS
  • Merck: 14,222
  • Ashby, J., et al.: Mutat. Res., 257, 229 (1991),
  • Short: IV/8A

安全信息

GHS Symbol
WGK Germany3
Hazard Codes T+,N T+;N T+,N,Xn,F
Hazard statements
  • H300 Fatal if swallowed 吞食致命
  • H310 Fatal in contact with skin 皮肤接触致命
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H330 Fatal if inhaled 吸入致命
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECSUE2275000
Precautionary statements
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P301+P310
  • P302+P350
  • P302+P352
  • P304+P340
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
  • P320 Specific treatment is urgent (see … on this label). 紧急具体治疗(见本标签上的)。
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P322 Specific measures (see …on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P361 Remove/Take off immediately all contaminated clothing. 立即去除/脱掉所有被污染的衣服。
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Signal word Danger
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S22 Do not breathe dust 不要吸入粉尘;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Risk Statements
  • R24 Toxic in contact with skin 与皮肤接触有毒
  • R26/28 Very toxic by inhalation and if swallowed 吸入及吞食都有剧毒
  • R50/53
  • R36 Irritating to eyes 刺激眼睛
  • R11 Highly flammable 非常易燃
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
UN Number 2757 2811
Storage condition APPROX 4°C 储存温度2-8℃
Restrict 剧毒化学品
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4108991

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 666 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   25,569,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 280 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TSCAT* Office of Toxic Substances Report.  (U.S. Environmental Protection
   Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460)
   Volume(issue)/page/year: FYI-OTS-0885-0443

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 750 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ASTTA8 ASTM Special Technical Publication.  (American Soc. for Testing
   Materials, 1916 Race St., Philadelphia, PA 19103)  No.1-    1911-
   Volume(issue)/page/year: (680),157,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bi

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 mg/disc
REFERENCE :
   JPFCD2 Journal of Environmental Science and Health, Part B: Pesticides, Food
   Contaminants, and Agricultural Wastes.  (Marcel Dekker, 270 Madison Ave.,
   New York, NY 10016)  V.B11-    1976-  Volume(issue)/page/year: 21,319,1986

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 2 gm/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 196,61,1988

TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - rat Embryo
DOSE/DURATION           : 117 ug/plate
REFERENCE :
   JJATDK JAT, Journal of Applied Toxicology.  (John Wiley & Sons Ltd., Baffins
   Lane, Chichester, W. Sussex PO19 1UD, UK)  V.

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 138,175,1984

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 500 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   12(Suppl 13),103,1988

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 350 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 191,99,1987

其他信息

  • MOL 文件:116-06-3.mol
  • PackingGroup:I
  • RTECS号:UE2275000
  • HazardClass:6.1(a)
  • 图谱信息:涕灭威(铁灭克)(116-06-3)红外图谱(IR2) 涕灭威(铁灭克)(116-06-3)红外图谱(IR1) 涕灭威(铁灭克)(116-06-3)核磁图( 13 CNMR) 涕灭威(铁灭克)(116-06-3)质谱(MS) 涕灭威(铁灭克)(116-06-3)核磁图( 1 HNMR)
  • 用途:属内吸性杀虫剂,主要用于防治棉花害虫如棉蚜、棉红蜘蛛、棉蓟马、象鼻虫等,也可防治甜菜、麻类及花卉害虫
  • 生产方法:将异丁烯、亚硝酸钠和盐酸进行二聚反应,生成2-氯-2-甲基-1-亚硝基丙烷二聚物。二聚物与甲硫醇钠反应,生成2-甲基-2-(甲硫基)丙醛肟。最后肟与异氰酸甲酯反应制得涕灭威。
  • 外观性质:有硫磺味的白色结晶。

系列性分类


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