CAS 3018-12-0 MFCD00040886-Dichloroacetonitrile 二氯乙腈 TAO{mole}

Dichloroacetonitrile 二氯乙腈

CAS 3018-12-0 MFCD00040886

化学结构图

SMILES: N#CC(Cl)Cl

化学属性

Mol. Formula	C₂HCl₂N
Mol. Weight	109.94
Refractive index	1.4390 to 1.4430
Boiling Point	-
Density	1.369
Flash Point	-
TSCA	No
Solubility	可混溶于乙醇、乙醚、甲醇。

别名和识别编码

Chemical Name	Dichloroacetonitrile
CAS Number	3018-12-0
PubChem Substance ID	18177
EC Number	221-159-4
Beilstein Registry Number	1739029
MDL Number	-
Reaxys-RN	1739029
Synonym	1,1-Dichlorocarbonitrile 2,2-Dichloroethanenitrile Acetnitrile, dichloro- Acetnitrile,dichloro- Acetonitrile, dichloro- DICHLOROACETONITRILE DICHLOROACETONITRILE, STANDARD FOR GC Dichloracetonitril Dichloroacetonitrile dichloroacetonitrile {} {} {} {Chemicalbook} dichloromethylcyanide {} {} {} {} {PubChem} dichloroacetonitrile {} {} {} {} {} {uni_hamburg} dichloro-acetonitrile {} {} {} {} {} {} {Chemicalbook} dichloro-acetonitril {} {} {} {} {} {} {} {uni_hamburg} Dichloromethyl cyanide {} {} {} {} {} {} {} {} {Chemicalbook} Dichloroacetonitrile, 98+% {} {} {} {} {} {} {} {} {} {} {} {} {} {uni_hamburg} Α,Α-二氯苯乙酮 Ω,Ω-二氯苯乙酮二氯乙腈二氯乙腈, 98+% 氰代二氯甲烷氰化二氯甲烷
Chemical Name Translation	二氯乙腈
Wiswesser Line Notation	NCYGG
LabNetwork Molecule ID	LN00194795
InChI	InChI=1S/C2HCl2N/c3-2(4)1-5/h2H
Canonical SMILES	-

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产品应用

用于有机合成，也用作溶剂。

安全信息

GHS Symbol

WGK Germany3

Hazard statements

H226 Flammable liquid and vapour 易燃液体和蒸气
H302 Harmful if swallowed 吞食有害
H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤

Personal Protective Equipment Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Hazard Codes 8 C

RTECSAL8465000

Precautionary statements

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
P233 Keep container tightly closed. ?保持容器密闭。
P240 Ground/bond container and receiving equipment. 与地面接触/连接集装箱和接受设备。
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment. 使用防爆电气/通风/照明/ .../设备。
P241+P242+P243
P242 Use only non-sparking tools. 只能使用无火花工具。
P243 Take precautionary measures against static discharge. 采取预防措施，防止静电放电。
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P301+P312
P301+P317
P301+P330+P331
P301+P330+P331+P310
P302+P361+P354
P303+P361+P353
P303+P361+P353+P310+P363
P304+P340
P304+P340+P310
P305+P351+P338
P305+P351+P338+P310
P305+P354+P338
P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
P316
P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
P330 Rinse mouth. 漱口
P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
P370+P378
P403+P235
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Signal word Danger

Safety Statements

S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
S25 Avoid contact with eyes 避免眼睛接触；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；

Risk Statements

R10 Flammable 易燃
R22 Harmful if swallowed 吞咽有害
R34 Causes burns 会导致灼伤
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险

UN Number 2920

Packing GroupII

Hazard Class8/3

Storage condition 0-6°C 4°C

Warnings 危化品目录(2015)

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 270 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   EVHPAZ EHP, Environmental Health Perspectives.  (U.S. Government Printing
   Office, Supt of Documents, Washington, DC 20402)  No.1-    1972-
   Volume(issue)/page/year: 69,183,1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 330 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   EVHPAZ EHP, Environmental Health Perspectives.  (U.S. Government Printing
   Office, Supt of Documents, Washington, DC 20402)  No.1-    1972-
   Volume(issue)/page/year: 69,183,1986

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Ovary
DOSE/DURATION           : 20800 nmol/L
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   5,1065,1985

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 50 mg/L
REFERENCE :
   MUREAV Mutation Res

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 nmol/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 5,447,1983

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 33 ug/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 8(Suppl
   7),1,1986

TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 200 ppm
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 7,325,1985

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Multiple routes
TEST SYSTEM             : Non-mammalian species
DOSE/DURATION           : 250 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 341,289,1995

TYPE OF TEST            : Sex chro

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 825 mg/kg
SEX/DURATION            : female 7-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - weaning or lactation index (e.g., #
   alive at weaning per # alive at day 4)
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 46,83,1987

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 325 mg/kg
SEX/DURATION            : female 6-18 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - cardiovascular
   (circulatory) system
   Reproductive - Specific Developmental Abnormalities - gastrointestinal
   system
   Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
   TJADAB Teratology, The International Journal of Abnormal Development. (Alan
   R. Liss, Inc., 41 E. 11th St., New York, NY 10003)  V.1-    1968-
   Volume(issue)/page/year: 35,58A,1987

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 825 mg/kg
SEX/DURATION            : female 7-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Effects on Newborn - live birth index (measured after birth)
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 46,83,1987

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Restrict 危险品

其他信息

Sigma Aldrich:3018-12-0(sigmaaldrich)
二氯乙腈价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 D2510 二氯乙腈 Dichloroacetonitrile 500G 3300元 2014/06/02 D2510 二氯乙腈 Dichloroacetonitrile 25G 300元 2010/05/25 A10612 二氯乙腈, 98+% Dichloroacetonitrile, 98+% 25g 787元
上游原料:氰乙酸 --> 丁二酰亚胺
毒性分级:高毒
TCI Shanghai:二氯乙腈 Dichloroacetonitrile,>;98.0%(GC)(3018-12-0)
MOL 文件:3018-12-0.mol
MSDS 信息:二氯乙腈(3018-12-0).msds
灭火剂:泡沫、二氧化碳、干粉、砂土
可燃性危险特性:明火可燃;受热分解放出有毒氯化物和氮氧化物
急性毒性:口服-大鼠 LD50： 330 毫克/公斤；口服-小鼠 LD50： 270 毫克/公斤
用途一:可作有机溶剂、作有机合成的中间体
图谱信息:二氯乙腈(3018-12-0)核磁图( 13 CNMR) 二氯乙腈(3018-12-0)核磁图( 1 HNMR) 二氯乙腈(3018-12-0)质谱(MS) 二氯乙腈(3018-12-0)红外图谱(IR1)
用途三:用于有机合成，也用作溶剂。
Alfa Aesar:二氯乙腈,98+% Dichloroacetonitrile, 98+%(3018-12-0)
外观性质:无色液体。
储运特性:库房通风低温干燥; 与氧化剂、食品添加剂、酸类分开存放
F:9-19
方法一:由N-氰代丁二酰亚胺与氰乙酸反应而得。
可混溶于乙醇、乙醚、甲醇。
用途二:用作医药、农药中间体
类别:有毒物品