N-(2-Bromobenzyl)-N,N-Dimethylethanaminium 4-Methylbenzenesulfonate N-(2-溴苄基)-N,N-二甲基乙胺-4-甲基苯磺酸盐
CAS 61-75-6 MFCD00038731
化学结构图
SMILES:
化学属性
| Mol. Formula | C11H17BrN.C7H7O3S |
|---|---|
| Mol. Weight | 414.40 |
别名和识别编码
| Chemical Name | N-(2-Bromobenzyl)-N,N-Dimethylethanaminium 4-Methylbenzenesulfonate |
|---|---|
| CAS Number | 61-75-6 |
| Synonym | (2-Bromobenzyl)ethyldimethylammonium p-toluenesulfonate Benzenemethanaminium, 2-bromo-N-ethyl-N,N-dimethyl-, salt with Bretylium tosylate ######## ASL-603 |
| MDL Number | MFCD00038731 |
| EC Number | 200-516-8 |
| Chemical Name Translation | N-(2-溴苄基)-N,N-二甲基乙胺-4-甲基苯磺酸盐 |
| Wiswesser Line Notation | ER B1K2&1&1 &OSWR D1 |
| LabNetwork Molecule ID | LN00188680 |
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分类
- Amines
- Aromatics
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Sulfur & Selenium Compounds
- {SNA} Adrenergics, Cell Biology, Cell Signaling and Neuroscience, Neuroscience, Neurotransmission, Neurotransmitters, Others
产品应用
- Bretylium tosylate has a biphasic response, initially inducing norepinephrine release followed by sympathetic ganglionic blockade. Bretylium tosylate is a class III antiarrhythmic agent and a competit
相关文献及参考
- Kuntzman, R., et al.: Clin. Pharmacol. Ther., 11, 829 (1970),
- Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971),
- Carter, J.E., et al.: Anal. Profiles Drug Subs., 9, 71 (1980),
安全信息
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 64 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PBPSDY Pharmacological and Biochemical Properties of Drug Substances. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.1- 1977- Volume(issue)/page/year: 2,148,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 43 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PBPSDY Pharmacological and Biochemical Properties of Drug Substances. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.1- 1977- Volume(issue)/page/year: 2,148,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 30 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PBPSDY Pharmacological and Biochemical Properties of Drug Substances. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.1- 1977- Volume(issue)/page/year: 2,148,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 160 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PBPSDY Pharmacological and Biochemical Properties of Drug Substances. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.1
