12(S)-HETE 12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic Acid

CAS 54397-83-0 MFCD00036916

化学结构图

54397-83-0
SMILES: CCCCC/C=C\C[C@H](O)/C=C/C=C\C/C=C\CCCC(O)=O

化学属性

Mol. FormulaC20H32O3
Mol. Weight320.47

别名和识别编码

Chemical Name12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid
CAS Number54397-83-0
Synonym (S)-12-HETE 12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid 12-HETE 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid 12-Hydroxyeicosatetraenoic Acid 12-L-Hydroxy-5,8,10,14-eicosatetraenoic Acid [S-(E,Z,Z,Z)]-12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
MDL NumberMFCD00036916
PubChem Substance ID24895806
Beilstein Registry Number2656104
EC Number200-578-6
Chemical Name Translation12(S)-Hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic Acid
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分类

  • Arachidonic Acid Cascade, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Fatty Acids and conjugates, Fatty Acyls, H, Hydroxy fatty acids,
  • {SNA} Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Fatty Acids and conjugates, Fatty Acyls, H, Hydroxy fatty acids, Lipids in Cell Signaling, Omega 6 fatty acids and derivatives, Oxylipins, Polyunsaturated, Unsaturated Fatty Acids and Derivatives, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学,

产品应用

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相关文献及参考

  • Nording, M.L. et al.: IEEE Sensors J., 10, 123 (2010); Pidgeon, G.P. et al.: Canc. Res., 62, 2721 (2002); Honn, K.V. et al.: Exp. Cell Res., 214, 120 (1994); Feldstein, A.E. et al.: J. Lipid Res., 51,
  • Zink, M.H., et al., 12-Lipoxygenase in porcine coronary microcirculation: implications for coronary vasoregulation. Am. J. Physiol. Heart Circ. Physiol. 280 , H693-H704, (2001)
  • Hagmann, W., Lipoxygenase in human tumor cells. Pathol. Oncol. Res. 3 , 83-88, (1997)
  • Szekeres, C.K., et al., Eicosanoid 12(S)-HETE activates phosphatidylinositol 3-kinase. Biochem. Biophys. Res. Commun. 275 , 690-695, (2000)

安全信息

WGK Germany1
Hazard Codes F F,Xi
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S7 Keep container tightly closed 保存在严格密闭容器中；
  • S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
Risk Statements
  • R11 Highly flammable 非常易燃
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
GHS Symbol
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P337+P313
  • P403+P235
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
Signal word Danger
Hazard statements
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H319 Causes serious eye irritation 严重刺激眼睛

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Lipids - Biochemicals and Reagents
  4. Fatty Acyls - Lipids
  5. Fatty Acids and conjugates - Fatty Acyls
  6. Unsaturated Fatty Acids and Derivatives - Fatty Acids and conjugates
  7. Polyunsaturated - Unsaturated Fatty Acids and Derivatives
  8. Omega 6 fatty acids and derivatives - Polyunsaturated
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Lipids - Biochemicals and Reagents
  4. Fatty Acyls - Lipids
  5. Fatty Acids and conjugates - Fatty Acyls
  6. Unsaturated Fatty Acids and Derivatives - Fatty Acids and conjugates
  7. Polyunsaturated - Unsaturated Fatty Acids and Derivatives
  8. Omega 6 fatty acids and derivatives - Polyunsaturated
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Lipids in Cell Signaling - Cell Signaling and Neuroscience
  5. Arachidonic Acid Cascade - Lipids in Cell Signaling
  6. Oxylipins - Arachidonic Acid Cascade

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