Imidazo(4,5-d)(1,3)diazepin-8-ol,3,4,7,8-tetrahydro-3-beta-D-ribofuranosyl-, (R)-
CAS 11033-22-0 MFCD00036884
化学结构图
SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2C(O)CNC=NC1=2
化学属性
| Mol. Formula | C11H16N4O5 |
|---|---|
| Mol. Weight | 284.31 |
别名和识别编码
| Chemical Name | Imidazo(4,5-d)(1,3)diazepin-8-ol,3,4,7,8-tetrahydro-3-beta-D-ribofuranosyl-, (R)- |
|---|---|
| Synonym | Coformycin (R)-3,4,7,8-Tetrahydro-3-beta-D-ribofuranosylimidazo(4,5-d)(1,3)diazepin-8-ol |
| CAS Number | 11033-22-0 |
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相关文献及参考
- [2]. Lukey T, et al. S-adenosylhomocysteine hydrolase activity, deoxyadenosine triphosphate accumulation, and competence of thymocyte and spleen leucocyte response to mitogens in coformycin-treated mice. Biochem Pharmacol. 1983 Apr 15;32(8):1399-406.
- [1]. Coformycin.
- [1]. Coformycin.
- [2]. Lukey T, et al. S-adenosylhomocysteine hydrolase activity, deoxyadenosine triphosphate accumulation, and competence of thymocyte and spleen leucocyte response to mitogens in coformycin-treated mice. Biochem Pharmacol. 1983 Apr 15;32(8):1399-406.
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 35 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 5,330,1981
