CAS 62-73-7 MFCD00036123-Dichlorvos 敌敌畏标准溶液 TAO{mole}

Dichlorvos 敌敌畏标准溶液

CAS 62-73-7 MFCD00036123

化学结构图

SMILES: COP(=O)(OC)OC=C(Cl)Cl

化学属性

Mol. Formula	C4H7Cl2O4P
Mol. Weight	220.98
Melting Point	-60°C
Boiling Point	140°C
Density	0.7915
Solubility	略溶于水. 1 G/100 ML
Stability	对光敏感
Flash Point	100 °C

别名和识别编码

Chemical Name	Dichlorvos
CAS Number	62-73-7
Alfabeta Name	DICHLOROVINYLDIMETHYLPHOSPHATE 22-,
MDL Number	MFCD00036123
Synonym	Astrobot {uni_hamburg} Dichlorophos 2,2-二氯乙烯基二甲基磷酸酯 Dichlofos Equigel Bre DEDEVAP BAYER 19 Phosvit 75 Vapona insecticide 2,2-DICHLOROVINYL DIMETHYL PHOSPHATE Apavap phosphoric acid, 2,2-dichloroethenyl dimethyl ester Cekusan DICHLORVOS DDVP (insecticide) DEDEVAP(R) Novotox 敌敌畏 SD-1750 O,O-Dimethyl O-2,2-dichlorovinyl phosphate DICHLORVOS-D6 (DIMETHYL-D6) 2,2-Dichlorovinyl dimethyl phosphate {Ch Phosphoric acid, 2,2-dichlorovinyl dimethyl ester 2,2-Dichloroethenyl dimethyl phosphate Vapona Nefrafos DICHLOROV Dedevap Dichlorovos Divipan O,O-二甲基-O-(2,2-二氯乙烯基)磷酸酯 {uni_ham Phosphorsäure-2,2-dichlorvinyl-di- o-(2,2-Dichlorvinyl)-O,O-dimethylphosphat Nuvan 7 Vinyl alcohol, 2,2-dichloro-, dimethyl phosphate Tas Derribante CHARGE Mopari {uni {C Dimethyl dichlorovinyl phosphate dimethyl 2,2-dichloroethen Estrosol { o,o-dimethyl 2,2-dichlorovinyl phospha {Chem {uni_ha 二氯酯 Canogard {uni_ Bibesol DDVP Dimethyl 2,2-dichlorovinyl phosphate {h 敌敌畏·久效磷·氰戊菊酯 Atgard V T (2,2-D Panaplate DICHLORVOS ( O,O-Dimethyl 2,2-dichlorovinyl phosphate (2,2-Dichloro-vinil)dimetil-fosfato BAY-19149 Dichlorman Atgard C {hazard
PubChem Substance ID	3039
EC Number	200-547-7
Beilstein Registry Number	1709141
Chemical Name Translation	敌敌畏标准溶液
Merck Number	13,3105
Wiswesser Line Notation	GYGU1OPO&O1&O1
LabNetwork Molecule ID	LN00160264
InChI	InChI=1S/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

敌敌畏具有熏蒸、胃毒和触杀作用，对咀嚼式口器害虫和刺吸式口器害虫均有良好的防效。敌敌畏的蒸气压较高，对害虫有很强的击倒力。施用后易分解、残效短期。
使用方法多种多样，简便易行。适用于防治棉花、果树、蔬菜、甘蔗、烟草茶、桑等作物上的多种害虫。对蚊、蝇等家庭卫生害虫。对蚊、蝇等家庭卫生害虫以及仓库害虫米象、谷盗等也有良好的防治效果。
校准仪器和装置；评价方法；工作标准；质量保证/质量控制；其他.

安全信息

Warnings IRRITANT 危化品目录(2015) 危险化学品

GHS Symbol

WGK Germany3

Hazard statements

H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
H330 Fatal if inhaled 吸入致命
H317 May cause an allergic skin reaction 可能导致皮肤过敏
H311 Toxic in contact with skin 皮肤接触中毒
H301 Toxic if swallowed 吞食有毒

Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

RTECSTC0350000

Precautionary statements

P273 Avoid release to the environment. 避免释放到环境中。
P301+P310
P284 Wear respiratory protection.? 佩戴呼吸保护装置。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。

Signal word Danger

Hazard Codes T+,N T;N,N,T,T+ T;N

Safety Statements

S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
S1/2 None 上锁保管并避免儿童触及；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；

Risk Statements

R26 Very toxic by inhalation 吸入极毒
R24/25 Toxic in contact with skin and if swallowed 皮肤接触及吞食都有毒
R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
R50 Very toxic to aquatic organisms 对水生生物极毒

UN Number 2783 2786

Storage condition 室温、干燥、避光. 储存温度2-8°C 干燥、避光.储存温度-20°C 室温储存 0-6°C

Restrict 剧毒化学品

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4120 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Gastrointestinal - tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-342,1989

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20600 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-342,1989

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2060 mg/kg/2Y-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Blood - leukemia
REFERENCE :
   JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB
   211, 1000 AE Amsterdam, Netherlands)  V.76-    1985-
   Volume(issue)/page/year: 82,157,1991

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10800 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APYPAY Acta Physiologica Polonica.  (Karger-Libri, POB CH-4009, Warszawa,
   Switzerland) V.1-41, 1950-90.  Volume(issue)/page/year: 32,507,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 22 mg/kg
TOXIC EFFECTS :
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - true cholinesterase
REFERENCE :
   JAFCAU Journal of Agricultural and Food Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1953-  Volume(issue)/page/year: 11,91,1963

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 15 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - other degenerative changes
   Blood - other changes
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - true cholinesterase
REFERENCE :
   APTSAI Acta Pharmacologica et Toxicologica, Supplementun.  (Munksgaard
   International Pub., POB 2148, DK-1016 Copenhagen K, Denmark)  No.1- 1947- 
   Volume(issue)/page/year: 49(5),67,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 18 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 65 mmol/L
REFERENCE :
   PSSCBG Pesticide Science.  (Blackwell Scientific Pub. Ltd., POB 88, Oxford,
   UK)  V.1-    1970-  Volume(issue)/page/year: 15,439,1984

TYPE OF TEST            : Cytogenetic a

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Serratia marcescens
DOSE/DURATION           : 25 mg/L
REFERENCE :
   ATXKA8 Archiv fuer Toxikologie.  (Berlin, Fed. Rep. Ger.)  V.15-31, 1954-74.
    For publisher information, see ARTODN.  Volume(issue)/page/year: 30,67,1972

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 12500 mg/L
REFERENCE :
   NTPTR* National Toxicology Program Technical Report Series.  (Research
   Triangle Park, NC 27709) No.206-  Volume(issue)/page/year: NTP-TR-342,1989

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 60 nmol/plate
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   33,458,1973

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 5 pph
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 40,19,1976

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1 gm/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 52,16

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 65 mg/kg
SEX/DURATION            : female 6-13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 39200 ug/kg
SEX/DURATION            : female 14-21 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - biochemical and metabolic
REFERENCE :
   NUPOBT Neuropatologia Polska.  (Ars-Polona, POB 1001, 00-068 Warsaw 1,
   Poland)  V.1-    1963-  Volume(issue)/page/year: 15,255,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 220 mg/kg
SEX/DURATION            : multigeneration
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
   Reproductive - Effects on Newborn - physical
   Reproductive - Effects on Newborn - delayed effects
REFERENCE :
   IJEREO International Journal of Environmental Health Research.  (Carfax
   Publishing Co., POB 25, Abingdon, Oxon. Ox14 3UE, UK) V.1-    1991-
   Volume(issue)/page/year: 5,239,1995

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - guinea pig
DOSE                    : 90 mg/kg
SEX/DURATION            : female 42-44 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - Central Nervous System
REFERENCE :
   NEREDZ Neurochemical Research.  (Plenum Pub. Corp., 233 Spring St., New
   York, NY 10013) V.1-    1976-  Volume(issue)/page/year: 19,569,1994

其他信息

毒性:大鼠急性经口LD 50 为80mg/kg（雄）、56mg/kg(雌），雄大鼠急性经皮LD 50 为107mg/kg，雌性为75mg/kg；小鼠急性吸入LC 50 为13.2mg/m 3 (4h)，大鼠吸入LC 50 为14.8mg/m 3 。雄大鼠90d饲喂试验的无作用剂量为1mg/kg。鲤鱼LC 50 为4mg/L（36h)、蓝鳃鱼LC 50 为1mg/L（24h)。对蜜蜂、瓢虫有毒。
用途:可用作家庭和公共场所的熏蒸剂，也适用于防治棉花、果树、蔬菜、烟、茶、桑等作物上的多种害虫
外观性质:纯品是无色有芳香气味的液体。有挥发性。
生产方法:脱氯化氢法敌百虫在碱性条件下脱氯化氢生成敌敌畏。操作时控制敌百虫水悬浮液含量为25%（也可用精制敌百虫母液，加适时的敌百虫固体），敌百虫与碱的配比为1:(1.35～1.4)，采用水和甲苯（二甲苯、苯）两个溶剂，反应温度50～60℃，反应时间20～25min，终点pH值7～8。这一反应使α-羟基膦酸酯重排成磷酸酯。反应结束静置分层，油层经薄膜蒸发回收溶剂，并得敌敌畏原油。直接合成法亚磷酸三甲酯的制备见杀虫畏的制备方法。敌敌畏的制备此法利用亚磷酸三甲酯与三氯乙醛反应，脱去一分子氯甲烷而合成，称perkow反应。操作时将亚磷酸三甲酯（或三氯乙醛）在常温下滴加到三氯乙醛（或亚磷酸三甲酯）中，所放出热量需冷却，控制滴加温度60℃，滴毕，于70℃保温90min，亚磷酸三甲酯与三氯乙醛的配比为1:1，收率94.53%。
杀虫剂单一组分标准液
HazardClass:6.1(a)
毒害物质数据:62-73-7(Hazardous Substances Data)
PackingGroup:II
20℃的蒸气压为1.6pa。室温下在水中的溶解度约为10g/L，在媒油中溶解2-3%，在碱性溶液或沸水中1h可完全水解，水解产物为磷酸氢二甲酯和二氯乙醛。
EPA化学物质信息:Phosphoric acid, 2,2-dichloroethenyl dimethyl ester(62-73-7)
NIST化学物质信息:Dimethyl-2,2-dichlorovinyl phosphate(62-73-7)
图谱信息:敌敌畏(62-73-7)红外图谱(IR1) 敌敌畏(62-73-7)质谱(MS) 敌敌畏(62-73-7)核磁图( 1 HNMR) 敌敌畏(62-73-7)核磁图( 13 CNMR)
RTECS号:TC0350000
MOL 文件:62-73-7.mol