Dyclonine hydrochloride 盐酸达克罗宁

CAS 536-43-6 MFCD00035386

化学结构图

536-43-6
SMILES: CCCCOc1ccc(C(=O)CCN2CCCCC2)cc1.Cl

化学属性

Mol. FormulaC18H28ClNO2
Mol. Weight326
SolubilitySoluble in water, chloroform, ethanol, acetone, and methanol.
Melting Point171.0 to 175.0 deg-C

别名和识别编码

Chemical NameDyclonine hydrochloride
MDL NumberMFCD00035386
CAS Number536-43-6
Synonym 1-(4-BUTOXYPHENYL)-3-(1-PIPERIDINYL)-1-PROPANONE HCL 1-(4-BUTOXYPHENYL)-3-(1-PIPERIDINYL)-1-PROPANONE HYDROCHLORIDE 1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanonhydrochloride 1-(4-丁氧基苯)-3-(1-呱啶基)-1-丙酮 1-(4-丁氧基苯)-3-(1-哌啶基)-1-丙酮盐酸盐 1-Propanone, 1-(4-butoxyphenyl)-3-(1-piperidinyl)-, hydrochloride 4'-Butoxy-3-piperidinopropiophenone hydrochloride 4'-丁氧基-3-哌啶基苯丙酮盐酸盐 4'-丁氧基-3-哌啶基苯丙酮盐酸盐;1-(4-丁氧基苯)-3-(1-呱啶基)-1-丙酮 4-n-Butoxy-beta-(1-piperidyl)propiophenone hydrochloride 4-n-butoxy-beta-(1-piperidyl)propiophenonehydrochloride 4’-butoxy-3-piperidino-propiophenonhydrochloride 4’-butoxy-3-piperidinopropiophenonehydrochloride C 5422 DYCLONINE DYCLONINE HCL DYCLONINE HYDROCHLORIDE Diclonia Dyclocainum Dyclone hydrochloride Dyclonine hydrocloride Dyclothane LABOTEST-BB LT00771942 P-267 Piperidine, 1-(2-(4-butoxybenzoyl)ethyl), hydrochloride S 154 Tanaclone c5422 diclonia dyclocainum dyclonehydrochloride dycloninehydrocloride dyclothane p-267 piperidine,1-(2-(4-butoxybenzoyl)ethyl),hydrochloride s154 tanaclone 盐酸达克罗宁 盐酸达克罗宁;达克罗宁 盐酸盐
PubChem Substance ID68304
EC Number208-633-6
Chemical Name Translation盐酸达克罗宁
Wiswesser Line NotationT6NTJ A2VR DO4 &GH
LabNetwork Molecule IDLN00197237
Reaxys-RN3744808
Merck Number3473
InChIInChI=1S/C18H27NO2.ClH/c1-2-3-15-21-17-9-7-16(8-10-17)18(20)11-14-19-12-5-4-6-13-19;/h7-10H,2-6,11-15H2,1H3;1H
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SA} Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, D, DJ - DZ, Drugs & Metabolites, Forensic and Veterinary Standards, Neat Compounds

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P310
  • P301+P312+P330
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P310
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H302 Harmful if swallowed 吞食有害
  • H315 Causes skin irritation 会刺激皮肤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
RTECSUG8750000
Signal word Danger
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Storage condition 0-10°C 储存温度-20°C 储存温度2-8℃
Packing GroupIII
Hazard Codes Xn
Hazard Class6.1(b)
UN Number 3249
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Risk Statements
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 240 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   2,616,1960

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 9500 ug/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Gastrointestinal - changes in structure or function of salivary glands
   Gastrointestinal - nausea or vomiting
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 115,419,1955

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 37 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 201 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 115,413,1955

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       :

TYP

其他信息

  • 图谱信息:盐酸达克罗宁(536-43-6)质谱(MS) 盐酸达克罗宁(536-43-6)红外图谱(IR2) 盐酸达克罗宁(536-43-6)红外图谱(IR1)
  • Sigma Aldrich:536-43-6(sigmaaldrich)
  • 储运特性:库房通风低温干燥
  • 毒性分级:高毒
  • 可燃性危险特性:热分解排出有毒氮氧化物, 氯化氢烟雾
  • 灭火剂:水,干粉、干砂、二氧化碳、泡沫、1211灭火剂
  • 上游原料:溴化钠
  • 用途一:用于表面麻醉。
  • Dyclonine HCl是Dyclonine的盐酸盐形式,是一种口服麻醉剂。
  • 刺激数据:皮肤-兔 1% 轻度; 眼睛-兔 2% 重度
  • 达克罗宁 盐酸盐
  • MOL 文件:536-43-6.mol
  • 急性毒性:腹腔-大鼠 LD50: 33 毫克/公斤; 腹腔-小鼠 LD50: 52 毫克/公斤
  • 类别:有毒物品

系列性分类


相关产品推荐