2-Amino-3-(2-hydroxyphenyl)propanoic acid 2-氨基-3-(2-羟基苯基)丙酸
CAS 2370-61-8 MFCD00021725
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分类
- {SNA} Analytical Standards,
- Amino Acids & Derivatives
- {SNA} Additional Standards, Analytical Standards, Chemical Biology, Chemical Class, Chemical Synthesis, Peptide Chemistry, Phenols, Tyrosine Derivatives, Unnatural Amino Acids & Derivatives, 分析/色谱
- {SNA} Chemical Class, Analytical Standards,
产品应用
- A metabolite of Phenylalanine
相关文献及参考
- Tsugita, A., et al.: Eur. J. Biochem., 124, 585 (1982),
- Li M, Carlson S, Kinzer JA, Perpall HJ., HPLC and LC-MS studies of hydroxylation of phenylalanine as an assay for hydroxyl radicals generated from Udenfriend's reagent. Biochem. Biophys. Res. Commun. 312 , 316-322, (2003)
- Klipcan L, Moor N, Kessler N, Safro MG., Eukaryotic cytosolic and mitochondrial phenylalanyl-tRNA synthetases catalyze the charging of tRNA with the meta-tyrosine. Proc. Natl. Acad. Sci. U. S. A. 106 , 11045-11048, (2009)
- Saravanabhavan G, Blais E, et al., A high performance liquid chromatography-electrochemical array method for the measurement of oxidative/nitrative changes in human urine. J. Chromatogr. A. 1217 , 3269-3274, (2010)
- Syslová K, Kačer P, Kuzma M, et al., LC-ESI-MS/MS method for oxidative stress multimarker screening in the exhaled breath condensate of asbestosis/silicosis patients. J. Breath Res. 4 , 017104, (2010)
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P264+P265
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P350
- P302+P352
- P302+P352+P332+P313+P362+P364
- P304+P340
- P305+P351+P338
- P305+P351+P338+P337+P313
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适,呼叫解毒中心或医生/医师。
- P319
- P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
- P332+P313
- P332+P317
- P337+P313
- P337+P317
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
- P362+P364
- P403+P233
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S37 Wear suitable gloves 戴适当手套;
- S36 Wear suitable protective clothing 穿戴适当的防护服;
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 320 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02426