1,3-Diiodo-5,5-dimethylhydantoin 1,3-二碘-5,5-二甲基海因

CAS 2232-12-4 MFCD00020867

化学结构图

2232-12-4
SMILES: CC1(C)C(=O)N(I)C(=O)N1I

化学属性

Mol. FormulaC5H6I2N2O2
Mol. Weight379.92
Melting Point198°C

别名和识别编码

Chemical Name1,3-Diiodo-5,5-diMethylhydantoin
Synonym 1,3-Diiodo-5,5-dimethylhydantoin {LY} 1,3-Diiodo-5,5-dimethylhydantoin {} {LY} 1,3-Diiodo-5,5-dimethylhydantoin {} {} {LY} 1,3-Diiodo-5,5-dimethylhydantoin {} {} {} {LY} 1,3-Diiodo-5,5-dimethylhydantoin {} {} {} {} {LY} 1,3-Diiodo-5,5-dimethylhydantoin {} {} {} {} {} {LY} 1,3-Diiodo-5,5-dimethylhydantoin {} {} {} {} {} {} {LY} 1,3-Diiodo-5,5-dimethylhydantoin {} {} {} {} {} {} {} {LY} 1,3-Diiodo-5,5-dimethylhydantoin {} {} {} {} {} {} {} {} {LY} 1,3-Diiodo-5,5-dimethylhydantoin {} {} {} {} {} {} {} {} {} {LY} 1,3-Diiodo-5,5-dimethylhydantoin {} {} {} {} {} {} {} {} {} {} {LY} 1,3-Diiodo-5,5-dimethylhydantoin {} {} {} {} {} {} {} {} {} {} {} {LY} 1,3-Diiodo-5,5-dimethylhydantoin {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,3-Diiodo-5,5-dimethylhydantoin {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,3-Diiodo-5,5-dimethylhydantoin {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,3-Diiodo-5,5-dimethylhydantoin {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,3-Diiod
MDL NumberMFCD00020867
Beilstein Registry Number24(4)1102
CAS Number2232-12-4
Reaxys-RN146040
PubChem Substance ID200534
Chemical Name Translation1,3-二碘-5,5-二甲基海因
InChIKeyRDZHCKRAHUPIFK-UHFFFAOYSA-N
LabNetwork Molecule IDLN00189197
InChIInChI=1S/C5H6I2N2O2/c1-5(2)3(10)8(6)4(11)9(5)7/h1-2H3
Canonical SMILESO=C(N1I)N(I)C(C)(C)C1=O
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分类

  • {SNA} Building Blocks, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Imidazolines/Imidazolidines
  • Building Blocks, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Imidazolines/Imidazolidines

相关文献及参考

  • 1. Iida, S.; Togo, H., Oxidative Conversion of Primary Alcohols, and Primary, Secondary, and Tertiary Amines into the Corresponding Nitriles with 1,3-Diiodo-5,5-dimethylhydantoin in Aqueous NH 3 Synlett 3 , 0407, (2007)
  • 2. Sidera, M.; et al., Iododesilylation of TIPS-, TBDPS-, and TBS-Substituted Alkenes in Connection with the Synthesis of Amphidinolides B/D Org. Lett. 13 , 4934, (2011) 摘要
  • 3. Baba, H.; Togo, H., Sulfonylamidation of alkylbenzenes at benzylic position with p-toluenesulfonamide and 1,3-diiodo-5,5-dimethylhydantoin Tetrahedron Lett. 51 , 2063, (2010)
  • 4. Chaikovskii, V. K.; et al., Evaluation of the reactivity and regioselectivity of superelectrophilic iodinating system Russ. J. Org. Chem. 45 , 1349, (2009)

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P220 Keep/Store away from clothing/…/combustible materials. 保持远离/贮存远离服装/....../可燃材料。
  • P221 Take any precaution to avoid mixing with combustibles/… 采取一切防范措施,避免与可燃物混合/...
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P317
  • P301+P330+P331
  • P301+P330+P331+P310
  • P302+P352
  • P302+P361+P354
  • P303+P361+P353
  • P303+P361+P353+P310+P363
  • P304+P340
  • P304+P340+P310
  • P305+P351+P338
  • P305+P351+P338+P310
  • P305+P354+P338
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P316
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P333+P313
  • P333+P317
  • P361+P364
  • P362+P364
  • P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
  • P370+P378
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P405 Store locked up. 上锁保管。
  • P420 Store away from other materials. 远离其他材料。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H272 May intensify fire; oxidizer 可能加剧火势;氧化剂。
  • H302 Harmful if swallowed 吞食有害
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
RTECSMU0970000
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Signal word Danger {} {} {} {} {} {} {TCI}
Storage condition 2-8°C, protect from light {LY} 2-8°C, protect from light <0°C <;0 {} {LY} 2-8°C, protect from light {} {} {LY} 2-8°C, protect from light {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect fro
UN Number 3085
Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Hazard Codes O,C,N
Risk Statements
  • R8 Contact with combustible material may cause fire 遇到易燃物会导致起火
  • R35 Causes severe burns 会导致严重灼伤
  • R50/53
Packing GroupII
Hazard Class5.1/8
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#05262

系列性分类


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