4',7-Dihydroxyflavone 7-羟基-2-(4-羟基苯基)-4H-苯并吡喃-4-酮
CAS 2196-14-7 MFCD00017694
化学结构图
SMILES: O=c1cc(-c2ccc(O)cc2)oc2cc(O)ccc12
化学属性
| Mol. Formula | C15H10O4 |
|---|---|
| Mol. Weight | 254.25 |
| Melting Point | 315-316 ºC |
| Density | 1.443 |
别名和识别编码
| Chemical Name | 4',7-Dihydroxyflavone |
|---|---|
| Synonym | 4',7-Dihydroxyflavone 4',7-Dihydroxyflavone; 7-Hydroxy-2-(4-hydroxyphenyl)chromen-4-one 4',7-dihydroxyflavone 4H-1-Benzopyran-4-one, 7-hydroxy-2-(4-hydroxyphenyl)- 7,4'-DHF 7,4'-Dihydroxyflavanone 7,4'-dihydroxyflavone 7-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one |
| CAS Number | 2196-14-7 |
| Wiswesser Line Notation | T66 BO EVJ CR DQ& IQ |
| Beilstein Registry Number | 0224356 |
| Chemical Name Translation | 7-羟基-2-(4-羟基苯基)-4H-苯并吡喃-4-酮 |
| LabNetwork Molecule ID | LN01360375 |
| PubChem Substance ID | 5282073 |
| InChI | InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-8,16-17H |
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相关文献及参考
- [2]. Liu C, et al. The Flavonoid 7,4'-Dihydroxyflavone Inhibits MUC5AC Gene Expression, Production, and Secretion via Regulation of NF-κB, STAT6, and HDAC2. Phytother Res. 2015 Jun;29(6):925-32.
- [1]. Liu C, et al. The Flavonoid 7,4'-Dihydroxyflavone Prevents Dexamethasone Paradoxical Adverse Effect on Eotaxin Production by Human Fibroblasts. Phytother Res. 2017 Mar;31(3):449-458.
- [1]. Liu C, et al. The Flavonoid 7,4'-Dihydroxyflavone Prevents Dexamethasone Paradoxical Adverse Effect on Eotaxin Production by Human Fibroblasts. Phytother Res. 2017 Mar;31(3):449-458.
- [2]. Liu C, et al. The Flavonoid 7,4'-Dihydroxyflavone Inhibits MUC5AC Gene Expression, Production, and Secretion via Regulation of NF-κB, STAT6, and HDAC2. Phytother Res. 2015 Jun;29(6):925-32.
安全信息
TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 38,67,1983
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 100 ug/plate REFERENCE : ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,401,1981
