Silybin 水飞蓟宾
CAS 22888-70-6 MFCD00017488
化学结构图
SMILES: COC1C=C(C=CC=1O)[C@@H]1OC2C=C(C=CC=2O[C@H]1CO)[C@@H]1OC2C=C(O)C=C(O)C=2C(=O)[C@H]1O |&1:9,18,21,33|
化学属性
| Mol. Formula | C25H17D5O10 |
|---|---|
| Mol. Weight | 487.4700 |
别名和识别编码
| Chemical Name | Silybin |
|---|---|
| Synonym | 水飞蓟素 |
| Chemical Name Translation | 水飞蓟宾 |
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相关文献及参考
- [2]. Kim TH, et al. Silibinin induces cell death through ROS-dependent down-regulation of Notch-1/ERK/Akt signaling in human breast cancer cells. J Pharmacol Exp Ther. 2014 Jan 28.
- [3]. Zhang S, et al. Silybin-mediated inhibition of Notch signaling exerts antitumor activity in human hepatocellular carcinoma cells. PLoS One. 2013 Dec 27;8(12):e83699.
- [4]. Khan AQ, et al. Silibinin Inhibits Tumor Promotional Triggers and Tumorigenesis Against Chemically Induced Two-Stage Skin Carcinogenesis in Swiss Albino Mice: Possible Role of Oxidative Stress and Inflammation. Nutr Cancer. 2013 Dec 23.
- [5]. Khazim K, et al. The antioxidant silybin prevents high glucose-induced oxidative stress and podocyte injury in vitro and in vivo. Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F691-700.
- [1]. Woo SM, et al. Silibinin induces apoptosis of HT29 colon carcinoma cells through early growth response-1 (EGR-1)-mediated non-steroidal anti-inflammatory drug-activ
