Diosmetin 香叶木素
CAS 520-34-3 MFCD00017425
化学结构图
SMILES: COc1ccc(-c2cc(=O)c3c(O)cc(O)cc3o2)cc1O
化学属性
| Mol. Formula | C16H12O6 |
|---|---|
| Mol. Weight | 300 |
| Melting Point | 256-258°C |
别名和识别编码
| Chemical Name | Diosmetin |
|---|---|
| MDL Number | MFCD00017425 |
| CAS Number | 520-34-3 |
| EC Number | 208-291-8 |
| Synonym | ',5,7-Trihydroxy-4'-methoxyflavone 4'-Methylluteolin 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one Luteolin 4'-methyl ether 2-(3-Hydroxy-4-methoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one 4'-METHOXY-5,7,3'-TRIHYDROXYFLAVONE 4'-Methylluteolin 5,7,3'-TRIHYDROXY-4'-METHOXYFLAVONE 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one 5,7-Trihydroxy-4-methoxyflavone, 4-Methylluteolin, 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one, Luteolin 4-methyl ether 5,7-Trihydroxy-4′-methoxyflavone, 4′-Methylluteolin, 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one, Luteolin 4′-methyl ether DIOSMETIN DIOSMETIN WITH HPLC DIOSMETIN(P) Diosmetin Luteolin 4'-methyl ether Pillon |
| Beilstein Registry Number | 294492 |
| Chemical Name Translation | 香叶木素 |
| PubChem Substance ID | 5281612 |
| LabNetwork Molecule ID | LN00200086 |
| InChI | InChI=1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3 |
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分类
- {SNA} A - D, Additional Standards, Alphabetical, Analytical Standards, Chemical Class, Chromatography, Citrus, Flavonoids, Flavonoids (Catechins), Galium, Life Sciences Standards, Mentha, Natural Compounds,
相关文献及参考
- [2]. Yu G, et al. Diosmetin ameliorates the severity of cerulein-induced acute pancreatitis in mice by inhibiting the activation of the nuclear factor-κB. Int J Clin Exp Pathol. 2014 Apr 15;7(5):2133-42.
- [1]. Liu B, et al. Diosmetin induces apoptosis by upregulating p53 via the TGF-β signal pathway in HepG2 hepatoma cells. Mol Med Rep. 2016 Jul;14(1):159-64.
- [1]. Liu B, et al. Diosmetin induces apoptosis by upregulating p53 via the TGF-β signal pathway in HepG2 hepatoma cells. Mol Med Rep. 2016 Jul;14(1):159-64.
- [2]. Yu G, et al. Diosmetin ameliorates the severity of cerulein-induced acute pancreatitis in mice by inhibiting the activation of the nuclear factor-κB. Int J Clin Exp Pathol. 2014 Apr 15;7(5):2133-42.
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- R22 Harmful if swallowed 吞咽有害
- S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
- P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
其他信息
- MOL 文件:520-34-3.mol
- 作用与用途:1. 经研究香叶木素具有升压的作用。 2. 香叶木素对铁氰化钾－鲁米诺体系的化学发光具有显著的增敏作用，试验结果表明：在碱性鲁米诺溶液中加入铁氰化钾溶液0.8S后，发光强度增大了0.5倍，3.85S后再缓慢下降；在碱性鲁米诺与铁氰化钾的混合溶液中，加入香叶木素，经0.55S后发光强度增大一倍多，后者的发光值改变超过前者。这充分说明香叶木素对铁氰化钾溶液氧化碱性鲁米诺的化学发光有较强的增敏作用。 3. 香叶木素可用于生产具有抗氧化、抗感染、抗休克等功效的功能性食品、化妆品和未来药物。一种抑制人CYP1A酶活力的天然黄酮类化合物。香叶木素具有抗诱变和抗变应性特性。
- 来源植物:香叶木素是从柠檬中提取得来的单体。在留兰香，蜘蛛香，等许多天然植物中也含有香叶木素。
- 分析方法:高效液相色谱法HPLC。
- 性状:黄色粉末，属于黄酮类化合物。
