• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Antioxidant and Free Radical Scavenge
• {SNA} Antioxidant and Free Radical Scavengers, Aspalathus linearis (Rooibos tea), Bioactive Small Molecule Alphabetical Index, Carthamus tinctorius (Safflower oil), Chamaemelum nobile (Chamomile tea), Fatty Acid Synthase (FAS) Inhibitors, Flavonoids, Flavonols, and Flavanols, Ginkgo biloba, Hypericum perforatum (St John's wort), L, Lavandula angustifolia (Lavendar tea), Linum usitatissimum (Flax), Metabolites, Inhibitors and Activators of Fatty Acid Metabolism, Ocimum basilicum (Basil), Phytochemicals by Chemical Classification, Phytochemicals by Plant (Food/Spice/Herb), Phytochemicals in Herbal Medicine or Traditional Chinese Medicine (TCM), Plantago ovata, 一氧化氮和细胞应激, 化学预防剂, 抗氧化剂和细胞保护剂,
• {SNA} Antioxidant an

产品应用

• 羟基黄酮衍生物，是强抗氧化剂和自由基清除剂，抗癌方面起重要作用。

相关文献及参考

• [2]. Abu-Elsaad N, et al. Protection against nonalcoholic steatohepatitis through targeting IL-18 and IL-1alpha by luteolin. Pharmacol Rep. 2019 Aug;71(4):688-694.
• [3]. Xiuwen Tang, et al. Luteolin inhibits Nrf2 leading to negative regulation of the Nrf2/ARE pathway and sensitization of human lung carcinoma A549 cells to therapeutic drugs. Free Radic Biol Med. 2011 Jun 1;50(11):1599-609.
• Anti-oxidant and radical scavenger in biological systems: Methods Enzymol., 234, 420 (1994).
• Merck: 14,5614
• Merck: 14,5614 Beilstein:18(5)5,296
• [1]. Ma L, et al. Luteolin exerts an anticancer effect on NCI-H460 human non-small cell lung cancer cells through the induction of Sirt1-mediated apoptosis. Mol Med Rep. 2015 Sep;12(3):4196-4202.
• [1]. Ma L, et al. Luteolin exerts an anticancer effect on NCI-H460 human non-small cell lung cancer cells through the induction of Sirt1-mediated apoptosis. Mol Med Rep. 2015 Sep;12(3):4196-4202.
• [2]. Abu-

安全信息

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. (China International Book
   Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.13-23,    1978-88. For
   publisher information, see ZYZAEU.  Volume(issue)/page/year: 16(2),11,1981

TYPE OF TEST            : Micronucleus test
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 246,205,1991

TYPE OF TEST            : Sex chromosome loss and nondisjunction
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 20 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 246,205,1991

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 246,205,1991

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 50 mg/kg
SEX/DURATION            : female 1 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   CCPTAY Contraception.  (Geron-X, Inc., POB 1108, Los Altos, CA 94022)  V.1-
   1970-  Volume(issue)/page/year: 42,467,1990

其他信息

• 微溶于水，溶于碱形成黄色溶液。