CAS 480-44-4 MFCD00016936-Acacetin 5,7-二羟基-2-(4-甲氧基苯基)-4H-1-苯并吡喃-4-酮 TAO{mole}

Acacetin 5,7-二羟基-2-(4-甲氧基苯基)-4H-1-苯并吡喃-4-酮

CAS 480-44-4 MFCD00016936

化学结构图

SMILES: COC1=CC=C(C=C1)C1=CC(=O)C2=C(C=C(O)C=C2O)O1

化学属性

Mol. Formula	C16H12O5
Mol. Weight	284.26
Melting Point	260-265 °C
Boiling Point	518.6 °C at 760 mmHg

别名和识别编码

Chemical Name	Acacetin
CAS Number	480-44-4
Synonym	Acacetin {LY} Acacetin {} {LY} Acacetin {} {} {LY} Acacetin {} {} {} {LY} Acacetin {} {} {} {} {LY} Acacetin {} {} {} {} {} {LY} Acacetin {} {} {} {} {} {} {LY} Acacetin {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Acacetin {} {} {} {} {} {} {} {} {LY} Acacetin {} {} {} {} {} {} {} {} {} {LY} Acacetin {} {} {} {} {} {} {} {} {} {} {LY} Acacetin {} {} {} {} {} {} {} {} {} {} {} {LY} Acacetin {} {} {} {} {} {} {} {} {} {} {} {} {LY} Acacetin {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Acacetin {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Acacetin {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Acacetin {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Acacetin {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Acacetin {} {} {} {} {} {} {} {} {} {} {} {}
MDL Number	MFCD00016936
Beilstein Registry Number	277879
EC Number	207-552-3
PubChem Substance ID	354334663
Chemical Name Translation	5,7-二羟基-2-(4-甲氧基苯基)-4H-1-苯并吡喃-4-酮
Merck Number	13
Wiswesser Line Notation	T66 BO EVJ CR DO1& GQ IQ
LabNetwork Molecule ID	LN01276215
Reaxys-RN	277879
Canonical SMILES	O=C1C=C(C2=CC=C(OC)C=C2)OC3=CC(O)=CC(O)=C13

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

VEGF expression inhibitor and tumor angiogenesis. A flavonoid with antiaggregatory activity in human blood.

安全信息

GHS Symbol

WGK Germany3

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P302+P352+P332+P313+P362+P364
P305+P351+P338
P305+P351+P338+P337+P313

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛
H335 May cause respiratory irritation 可能导致呼吸道刺激

RTECSDJ3002000

Signal word

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes Xi

Safety Statements

S36 Wear suitable protective clothing 穿戴适当的防护服；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；

Risk Statements

R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 933 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 32,210,1969

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 933 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 32,210,1969

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,401,1981

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 50 mg/kg
SEX/DURATION            : female 1 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   CCPTAY Contraception.  (Geron-X, Inc., POB 1108, Los Altos, CA 94022)  V.1-
   1970-  Volume(issue)/page/year: 42,467,1990

其他信息

F:3-8-10
Sigma Aldrich:480-44-4(sigmaaldrich)
MOL 文件:480-44-4.mol